Broomall, Pennsylvania Clinical Trials

A listing of Broomall, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 72 clinical trials
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group 36 week multicenter Phase 2 study of two doses of CT1812 in adults with mild to moderate Alzheimer's Disease (AD).

University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 20 Sep, 2024
  • +10 other locations
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

tumor resection
gliosarcoma
monoclonal antibodies
major surgery
growth factor
Hospital of the University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Test the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

The purpose of the study is to test the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

antibiotic
antibiotic therapy
bimekizumab
hidradenitis
antibiotics
Hs0004 50150
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification

Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions

University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

This is a pilot study using cytotoxic T lymphocytes (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Gamma-capture system will be effective in decreasing specific viral load in patients with BK virus viremia and BK virus-associated symptoms post-allogeneic hematopoietic stem cell transplantation (HSCT), renal transplantation, and chemotherapy.

Children's Hospital of Philadelphia
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test2a
 (8.8 away) Contact site
  • 0 views
  • 21 Nov, 2024
  • 1 location
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
pick's disease
aphasia
progranulin
University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
alzheimer's disease
flortaucipir
positron emission tomography
mini-mental state examination
University of Pennsylvania Heath System
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
API Trial-T2

API Trial-T12

Test AP Sit1
 (8.8 away) Contact site
  • 0 views
  • 18 Sep, 2024
  • 1 location