Broomall, Pennsylvania Clinical Trials

A listing of Broomall, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 72 clinical trials
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged 2 to < 15 years old, with Sickle Cell Disease. The primary objective is to evaluate the effect of voxelotor on the TCD (Transcranial Doppler Ultrasound) measurements in SCD participants in this age range.

gbt440
cerebral blood flow
anemia
transcranial doppler ultrasonography
voxelotor
Children's Hospital of Philadelphia
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +34 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

marginal zone lymphoma
malt
lymphoma
systemic therapy
cyclophosphamide
Perelman Center for Advanced Medicine - Abramson Cancer Center University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +35 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

connective tissue disease
ventricular septal defect
patent ductus arteriosus
heart disease
atrial septal defect
Lankenau Medical Center
 (4.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +210 other locations
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test1a
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
API Trial-T1

API Trial-T1

Test AP Sit1
 (8.8 away) Contact site
  • 0 views
  • 18 Sep, 2024
  • 1 location
PCSK9i in AAA123

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test2a
 (8.8 away) Contact site
  • 0 views
  • 20 Nov, 2024
  • 1 location
PCSK9i in AAA123  

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test2a
 (8.8 away)
  • 0 views
  • 18 Mar, 2025
  • +1 other locations
PCSK9i in AAA1234

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test1a
 (8.8 away) Contact site
  • 0 views
  • 04 Mar, 2025
  • +1 other locations
PCSK9i in AAA1235

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test1a
 (8.8 away) Contact site
  • 0 views
  • 04 Mar, 2025
  • +1 other locations
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

estimated creatinine clearance
SARS
cyclosporin a
cyclosporine
acute respiratory syndrome (sars)
University of Pennsylvania
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location