Glendora, California Clinical Trials

A listing of Glendora, California clinical trials actively recruiting patient volunteers.

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Found 46 clinical trials
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

This phase I trial studies the side effects and best dose of chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain in treating patients with MPP2+ glioblastoma that has come back (recurrent) or that is growing, spreading, or getting worse (progressive). Vaccines made from a gene-modified virus may …

serum pregnancy test
tumor cells
measurable disease
absolute neutrophil count
glioma
City of Hope Medical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

platelet transfusion
serum testosterone
glomerular filtration rate
ejection fraction
bilateral orchiectomy
Research Site
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

cancer
measurable disease
prostate cancer
metastatic cancer
metastatic castration-resistant prostate cancer
City of Hope Comprehensive Cancer Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

This phase II trial studies how well total marrow and lymphoid irradiation works as a conditioning regimen before hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute leukemia. Total body irradiation can lower the relapse rate but has some fatal side effects such as irreversible damage to normal internal …

tacrolimus
radionuclide ventriculography
karnofsky performance status
ejection fraction
gilbert's syndrome
City of Hope Medical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

lymphoma
blood count
platelet transfusion
MRI
bone marrow infiltration
City of Hope Comprehensive Cancer Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

solid tumor
kras g12c mutation
kras
metastatic malignant solid tumor
solid tumour
City of Hope Comprehensive Cancer Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +7 other locations