Glendora, California Clinical Trials

A listing of Glendora, California clinical trials actively recruiting patient volunteers.

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Found 45 clinical trials
Multi-center Open-label Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)

Primary Objectives: To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV) To evaluate the pharmacokinetics (PK) of SC and IV isatuximab Secondary Objectives: To estimate absolute bioavailability of SC and IV isatuximab To measure receptor occupancy (RO) after isatuximab SC versus IV administration To assess …

proteasome inhibitor
lenalidomide
measurable disease
corticosteroids
parenteral administration
Investigational Site Number 8400002
 (4.6 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +13 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
dulaglutide
body mass index
tirzepatide
Valley Clinical Trials, Inc.
 (3.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

Primary Objective: To determine the maximum tolerated dose (MTD) of SAR442257 administered as a single agent in patients with relapsed and refractory multiple myeloma (RRMM) and refractory non-Hodgkin lymphoma (RR-NHL), and determine the recommended Phase 2 dose (RP2D) Secondary Objectives: To characterize the safety profile of SAR442257 To characterize the …

excisional biopsy
hair thinning
chronic lymphocytic leukemia
lymphoma
cutaneous t-cell lymphoma
Investigational Site Number 8400001
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

proteasome inhibitor
ixazomib
lenalidomide
daratumumab
measurable disease
Investigational Site Number 8400002
 (4.6 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +7 other locations
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to three dose levels in adult participants aged 18 to 45 years with moderate to severe acne. This trial will consist of a …

Empire Clinical Research - Pomona- Site Number : 8400055
 (7.8 away) Contact site
  • 0 views
  • 29 Nov, 2025
  • +30 other locations
A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

carcinoma
karnofsky performance status
renal cell carcinoma
Research Site 2
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

This phase III trial studies how well a telehealth self-management program works in improving survivorship care and outcomes in stage I-III non-small cell lung cancer or colorectal cancer survivors. Survivor self-management program focuses on coaching patients on follow-up care after cancer treatments. Participating in the program may improve knowledge and …

stage ii colorectal cancer ajcc v8
stage ia3 lung cancer ajcc v8
stage i lung cancer ajcc v8
stage ib lung cancer ajcc v8
cancer
City of Hope Medical Center
 (6.4 away) Contact site
  • 4 views
  • 19 Feb, 2024
  • 1 location
Remotivation Process for Improving Adherence to Lymphedema Treatment Programs in Patients With Breast Cancer-Related Lymphedema

This trial studies how well the Remotivation Process in an occupational therapy program works in improving adherence to lymphedema treatment programs in patients with breast cancer-related lymphedema. Lymphedema treatment programs are well developed and effective, but adherence to these programs are an issue. The Remotivation Process is a series of …

breast carcinoma
lymphedema
breast cancer
carcinoma
cancer
City of Hope Medical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

oxaliplatin
PCR test
irinotecan
fluoropyrimidine
colorectal cancer
City of Hope
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

This phase I trial studies the side effects and best dose of chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain in treating patients with MPP2+ glioblastoma that has come back (recurrent) or that is growing, spreading, or getting worse (progressive). Vaccines made from a gene-modified virus may …

mpp2
malignant glioma
expression by immunohistochemistry
glioblastoma multiforme
recurrent disease
City of Hope Medical Center
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location