a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1927 clinical trials
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

monoclonal antibodies
nasal swab
nasopharyngeal swab
cancer
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 2 locations
VARA (Virtual and Augmented Reality Applications in Rehabilitation): Motor Rehabilitation Protocol With GRAIL for Patients Affected by Hemiparesis

The main goal of the study is to verify the efficacy of the GRAIL system in respect to the walking pattern improvement in a population of hemiparetic subjects. In particular, the specific goals will be: increase in walking symmetry and a better distribution among the time of stance and swing.

hemiparesis
weakness
  • 0 views
  • 19 Feb, 2024
  • 1 location
Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States  

In this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor for physiological and biochemical sensing; a conversational virtual human platform to evoke naturalistic social …

  • 0 views
  • 19 Aug, 2025
  • 2 locations
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

This study attempts to treat these diseases using T cells genetically modified with a 4th generation lentiviral chimeric antigen receptor (4SCAR fused with an inducible apoptotic caspase 9 domain) targeting CD276 (B7-H3).

immunohistochemistry
solid neoplasm
serum bilirubin
antibody therapy
metastasis
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT

There is however often poor tumour control with this technique due to the low doses given. Stereotactic Radiosurgery (SRS), a form of focused radiotherapy which is given to patients who have a limited number of brain metastases, gives a higher radiation dose to the metastases resulting in better target lesion …

stereotactic radiosurgery
whole brain radiotherapy
whole-brain radiotherapy
metastasis
treatment regimen
  • 0 views
  • 19 Feb, 2024
  • 1 location
Nivolumab Ipilimumab and Chemoradiation in Treating Patients With Locally Advanced Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. A locally unresectable tumor (locally advanced pancreatic cancer (LAPC)) is present in 30% of the cases and is defined as a surgically unresectable tumor encasing the adjacent arteries [celiac …

teratogenicity
treatment regimen
tumor burden
gilbert's syndrome
immunosuppressant
  • 0 views
  • 24 Nov, 2025
  • 1 location
SubsTRate OxidatioN in Girls

This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight. In addition, subjective appetite will be measured throughout the assessment periods.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Treatment With CSL312 in Adults With Coronavirus Disease 2019 (COVID 19)

This is a prospective, phase 2, multicenter, randomized, double blind, placebo controlled, parallel group study to assess the safety and efficacy of CSL312 administered intravenously, in combination with standard of care (SOC) treatment, in patients with Coronavirus disease 2019 (COVID 19)

oximetry
chest ct
administered intravenously
coronavirus infection
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neoadjuvant of Sintilimab Combined With Chemotherapy for Resectable NSCLC neoSCORE

This is a Phase 2, prospective, randomized, open-Label, single-center international study that assesses the efficacy and safety of neoadjuvant therapy with different cycles of sintilimab combined with chemotherapy for resectable NSCLC.

unstable angina
blood test
liver disease
transient ischemic attack
tuberculosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Tango for Alzheimer's Disease Patients' Caregivers

The goal of the project is to determine the extent to which indices of inflammatory biomarkers, cognition and mood, are influenced by a partnered, dance-based intervention vs control condition in African American (AA) female family caregivers, at high risk for Alzheimer's disease (AD).

alzheimer's disease
  • 24 views
  • 19 Feb, 2024
  • 1 location