a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1927 clinical trials
Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide

Compared with non-small-cell lung cancer (NSCLC) SCLC has a unique natural history with a shorter doubling time, higher growth fraction, earlier development of widespread metastases, and uniform initial response to chemo- or radiotherapy.

solid organ transplant
brain metastasis
systemic therapy
cns metastases
tuberculosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors

An ascending dose study in patients with solid tumors to evaluate the safety, tolerability, pharmacodynamics and efficacy of APG-1387 in combination with toripalimab. A phase II study of 3 cohorts will be included.

immunohistochemistry
antineoplastic
brain metastasis
neuropathy
alopecia
  • 0 views
  • 19 Feb, 2024
  • 1 location
JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

This is a Phase 1 study of JSI-1187 as monotherapy and in combination with dabrafenib for the treatment of advanced solid tumors with MAPK pathway mutations, including mutations that cause MAPK pathway hyperactivation.

investigational treatment
brain metastasis
gene fusion
serum pregnancy test
dabrafenib
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Caterpillar Arterial Embolization Device Post-Market Study

The primary objective of this study is to evaluate the performance and safety of the Caterpillar Arterial Embolization Device when used for arterial embolization in the peripheral vasculature in a real world, on-label application.

  • 0 views
  • 19 Feb, 2024
  • 12 locations
Neoadjuvant RCT Versus CT for Patients With Locally Advanced Potentially Resectable Adenocarcinoma of the GEJ

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone fr patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)

estrogen
kidney function test
flot regimen
oxaliplatin
progestogen
  • 0 views
  • 19 Feb, 2024
  • 1 location
Maintenance Treatment of Toripalimab(JS001) in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma

This study is a multicenter, single-arm, open, phase clinical study to evaluate the safety and efficacy of Toripalimab(JS001) monoclonal injection after chemotherapy in combination with Endostar for Locally Advanced or Metastatic Mucosal Melanoma.

melanoma
oral contraceptives
mucosal melanoma
maintenance treatment
toripalimab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Efficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome

This is a prospective, open-label, randomized, two-arm clinical trial conducted to evaluate the safety and efficacy of romiplostim in comparison with eltrombopag in the treatment of thrombocytopenia in patients with Wiskott-Aldrich syndrome

eltrombopag
thrombocytopenia
platelet count
wiskott-aldrich syndrome
romiplostim
  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of Food on the Pharmacokinetics of ASTX660 in Healthy Volunteers

This is a Phase 1, single-dose, open-label, randomized, three-period, three-way crossover study in which healthy adult participants will receive three separate single-dose administrations of ASTX660 capsules under three different conditions.

oophorectomy
tubal ligation
systolic blood pressure
hysterectomy
body mass index
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation

This is a Phase 1 randomized study to evaluate the safety, tolerability and efficacy of IV Ampion in improving the clinical course and outcomes of patients hospitalized with COVID-19 infection who require supplemental oxygen.

oximetry
acute respiratory syndrome (sars)
SARS
covid-19
oxygen supplementation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study

A mucosal melanoma postoperative adjuvant treatment of multicenter, randomized, double-blind, placebo-controlled phase II study, evaluation of mucosal melanoma patients accept completely resected, Toripalima Combined with Temozolomide and Cisplatin postoperative adjuvant therapy efficacy and safety

oral contraceptives
metastasis
adjuvant
temozolomide
melanoma
  • 0 views
  • 19 Feb, 2024
  • 1 location