Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8030 clinical trials
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients with uterine serous or carcinosarcoma histology. The investigators hypothesize that short course pelvic radiation will have an acute and late grade 3-4 …

neutrophil count
endometrial cancer
cancer
adenocarcinoma
carcinosarcoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study With Pembrolizumab for Non-small Cell Lung Cancer (NSCLC)

This study is a randomized, national multicenter clinical study which is designed to compare the efficacy of the safety and efficacy of treatment every 3 weeks or 6 weeks in (Non-small-cell-cell cancer, NSCLC) subjects without systematic treatment who used Pembrolizumab after 6 cycles of combined chemotherapy estimated with stable efficacy …

  • 0 views
  • 19 Feb, 2024
  • 1 location
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

A commercial liquid biopsy (circulating tumor DNA) NGS test will be provided to study participants free of charge.

pembrolizumab
systemic therapy
stage iv non-small cell lung cancer
proto-oncogene tyrosine-protein kinase ros
EGFR
  • 0 views
  • 19 Feb, 2024
  • 28 locations
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

recurrent glioblastoma
glioblastoma multiforme
renal function
glioblastoma
niraparib
  • 0 views
  • 19 Feb, 2024
  • 1 location
Intravesical Gemcitabine and Docetaxel for BCG na ve Non-muscle Invasive Bladder Cancer

A single-arm, two-stage, open-label, phase 2 study investigating the safety and efficacy of intravesical gemcitabine/docetaxel for bacillus Calmette-Guerin (BCG)-nave patients with non-muscle invasive bladder cancer (NMIBC). All participants will receive an induction course of gemcitabine/docetaxel instillations followed by maintenance instillations if initial efficacy is seen.

oophorectomy
bilateral salpingectomy
bcg vaccine
intravesical bcg therapy
bladder carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer. Methods: A Randomized Controlled Trial was designed to collect the perioperative data on consecutive patients undergoing lung resection for primary lung …

enhanced recovery after surgery
lung operation
lung surgery
pulmonary resection
lung cancer
  • 18 views
  • 19 Feb, 2024
  • 1 location
Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer

The addition of durvalumab to total neoadjuvant therapy (TNT) in locally advanced rectal cancer may improve the pathological complete response rate. The induction platinum-based chemotherapy may increase the neoantigen formation together with the chemoradiotherapy period.

live vaccine
non-melanoma skin cancer
organ transplantation
fluorouracil
hysterectomy
  • 0 views
  • 19 Feb, 2024
  • 10 locations
Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk

Mechanistic data show that compounds in fruits and vegetables have anti-inflammatory and anti-carcinogenic properties that can reduce breast cancer risk. However, observational and interventional studies have provided mixed results, and a recent report by the American Institute for Cancer Research (AICR) concludes that the data are insufficient but suggestive that …

pabc
dietary intervention
carotenoids
dietary counseling
breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer

Comparing preventive effect of myocardial global longitudinal strain-based cardioprotective stragety (angiotensin receptor blocker prophylaxis) with left ventricular ejection fraction-based strategy in breast cancer patients treated with adjuvant trastuzumab.

immunomodulators
breast cancer
anthracycline
her2+ breast cancer
her2-positive breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of CN1

This study is the first-in-human clinical trial of CN1 to evaluate the safety, tolerability, pharmacokinetic (PK) profile and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma. This study will provide a basis for further clinical development of CN1.

b-cell lymphoma
solid tumour
lymphoma
  • 0 views
  • 19 Feb, 2024
  • 1 location