Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8030 clinical trials
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2

This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with neurofibromatosis type 2 (NF2) with associated progressive tumors of vestibular schwannomas (VS), non-vestibular schwannomas (non-VS), meningiomas, and ependymomas. This Master Study is being conducted as a "basket" study that may allow …

bilateral tubal ligation
meningiomatosis
conventional mri
brigatinib
conventional imaging
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Combination Immunotherapy Targeting Sarcomas

The aim of this clinical trial is to assess the feasibility, safety and efficacy of a combination low dose chemotherapy and immunotherapy in patients who have sarcoma that is relapsed or late staged. Another goal of the study is to assess the safety and efficacy of the therapy that combines …

steroid hormone
recurrent sarcoma
immunosuppression
pulse oximetry
creatinine clearance rate
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

This early phase I trial studies the feasibility of giving memantine for the reduction of cognitive impairment after radiation therapy in pediatric patients with central nervous system tumors. Memantine may reduce the effects of radiation therapy on memory and thinking.

memantine
effects of radiation therapy
pediatric
cancer
direct bilirubin
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

ki-ras
metastatic malignant solid tumor
kras g12c mutation
solid tumour
solid tumor
  • 0 views
  • 19 Feb, 2024
  • 8 locations
Thyroid Cancer and Photoacoustic Imaging

In addition, we would like to confirm the relationship between the results of photoacoustic imaging and histopathologic findings when thyroid nodules were diagnosed as thyroid cancer.

photoacoustic imaging
thyroid nodule
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX)

Control arm will be paclitaxel in combination with cetuximab, treatment included in the guidelines of the Spanish Society of Medical Oncology.

leptomeningeal metastases
corticosteroids
neuropathy
skin disorder
major surgery
  • 0 views
  • 19 Feb, 2024
  • 20 locations
Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: Ipatasertib Atezolizumab

lymphadenectomy
colony stimulating factor
anticoagulants
granulocyte colony stimulating factor
ipatasertib
  • 0 views
  • 19 Feb, 2024
  • 1 location
cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation

The objective is to screen and monitor the efficacy of cfDNA methylation in patients with stage I lung cancer after ablation, to compare the similarities and differences of cfDNA methylation between surgical treatment and ablation in patients with stage I lung cancer, and to look for new indicators to assess …

cfdna
cancer
ct scan chest
chest ct
lung cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

This phase I/II trial studies the side effects and best dose of cabozantinib when given with radiation therapy and how well it works in treating patients with sarcoma of the extremities. Cabozantinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving …

colony-stimulating factors
human chorionic gonadotropin
bone metastases
ct scan
hair thinning
  • 0 views
  • 19 Feb, 2024
  • 1 location
Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

rectal cancer
adenocarcinoma
cancer
proctoscopy
adenocarcinoma of rectum
  • 0 views
  • 19 Feb, 2024
  • 1 location