Chemoradiotherapy Clinical Trials

A listing of Chemoradiotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 223 clinical trials
Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11)

The purpose of this study is to evaluate the efficacy and safety of pembrolizumab plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer. The primary hypotheses are that pembrolizumab plus concurrent chemoradiotherapy is superior to placebo plus concurrent chemoradiotherapy with respect to progression-free …

pembrolizumab
external beam radiotherapy
systemic therapy
carcinoma
concurrent radiochemotherapy
  • 0 views
  • 19 Feb, 2024
  • 14 locations
Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy (CONCERT)

It seeks to answer the following key questions:When compared to sequential treatment, does concurrent chemoradiotherapy increase disease-free survival?What effects does concurrent treatment have on post-operative look, quality of life, and side effects including arm swelling (lymphoedema)?

  • 0 views
  • 13 Jun, 2025
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC.

organ transplantation
carcinoma
corticosteroids
irreversible toxicity
induction chemotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

egfr blocker
nasopharyngeal carcinoma
carcinoma
concurrent radiochemotherapy
nimotuzumab
  • 4 views
  • 19 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma

This is a prospective single-arm study of endoscopic resection (ER) following concurrent chemoradiotherapy for stage I esophageal squamous cell carcinoma, to find if the treatment combination is useful by assessing its safety and efficacy.

carcinoma
endoscopic resection
esophageal squamous cell carcinoma
bone metastases
bone scan
  • 0 views
  • 19 Feb, 2024
  • 1 location
Durvalumab(MEDI4736) After chemoRadioTherapy(DART) for NSCLC-a Translational and Biomarker Study

The main aim is to identify and describe biomarkers in different sample types related to chemoradiation followed by durvalumab treatment for stage III PD-L1 negative and positive non-small cell lung cancer (NSCLC) patients' eligible for curatively intended chemoradiation.

lung cancer
neutrophil count
non-small cell lung cancer
stage iii non-small cell lung cancer
pet/ct scan
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer

This is a randomised, double-blinded, placebo-controlled, multi-center phase III trial, comparing the efficacy and safety of treatment with Camrelizumab (SHR-1210) + definitive chemoradiotherapy(dCRT) vs placebo+dCRT for locally advanced esophageal cancer patients in China. Camrelizumab (SHR-1210) is a humanized anti-PD1 IgG4 monoclonal antibody.

monoclonal antibody therapy
esophageal cancer
squamous cell carcinoma of esophagus
shr-1210
antibody therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Efficacy of Adjuvant Chemotherapy in Locally Advanced Cervical Cancer

The aim of this trial was to evaluate the efficacy of adjuvant chemotherapy in the locally advanced cervical cancer with residual lesions after concurrent chemoradiation therapy.

cervical cancer stage
carcinoma
adjuvant chemotherapy
adenosquamous carcinoma
cervical cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

carcinoma
adenosquamous carcinoma
adenocarcinoma
cervical cancer
squamous cell carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer

Standard chemoradiation, followed by surgery are standard treatment plan for patients suffering from pancreatic adenocarcinoma. Due to damage to the surrounding healthy tissue caused by standard radiation, this study uses a new type of radiation plan- pulsed low-dose rate (PLDR) radiation , in combination with chemotherapeutic drug, gemcitabine, given weekly …

kidney function tests
celiac disease
metastatic pancreatic cancer
adenocarcinoma
celiac
  • 0 views
  • 24 Nov, 2025
  • 1 location