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Found 4 clinical trials
Pyrotinib Trastuzumab Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

This study aims to evaluate the efficacy and safety of pyrotinib in combination with trastuzumab, pertuzumab and nab-paclitaxel as neoadjuvant therapy in early stage or locally advanced HER2-positive breast cancer.

erbb2 gene amplification
invasive breast cancer
emtansine
breast carcinoma
pertuzumab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

neutrophil count
primary lesion
invasive breast cancer
trastuzumab
cancer chemotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC.

This is a Phase II, open-label, randomized controlled umbrella trial evaluating the efficacy and safety of multiple targeted treatment in patients with metastaticTNBC.

measurable disease
solid tumour
pyrotinib
targeted therapy
capecitabine
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation

To Observe the Efficacy and Safety of Pyrotinib Maleate in Patients With Advanced HER2 Variation Colorectal Cancer

neutrophil count
12 lead electrocardiogram
pyrotinib
liver metastasis
colorectal cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location