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Found 4 clinical trials
Pyrotinib Trastuzumab Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

This study aims to evaluate the efficacy and safety of pyrotinib in combination with trastuzumab, pertuzumab and nab-paclitaxel as neoadjuvant therapy in early stage or locally advanced HER2-positive breast cancer.

HER2
trastuzumab
erbb2 gene amplification
immunohistochemistry
progesterone
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate …

HER2
platelet count
trastuzumab
bisphosphonate
her2+ breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC.

This is a Phase II, open-label, randomized controlled umbrella trial evaluating the efficacy and safety of multiple targeted treatment in patients with metastaticTNBC.

stage iv breast cancer
HER2
measurable disease
targeted therapy
pyrotinib
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation

To Observe the Efficacy and Safety of Pyrotinib Maleate in Patients With Advanced HER2 Variation Colorectal Cancer

absolute neutrophil count
HER2
platelet count
trastuzumab
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location