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Found 2 clinical trials
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

Patients with refractory and/or recurrent solid tumor have poor prognosis despite complex multimodel therapy and therefore, novel approaches are urgently needed. This study attempts to treat these diseases using T cells genetically modified with a 4th generation lentiviral chimeric antigen receptor (4SCAR fused with an inducible apoptotic caspase 9 domain) …

monoclonal antibodies
platelet count
blood transfusion
serum bilirubin
solid neoplasm
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

Total marrow and lymphoid irradiation may allow a greater dose of radiation to be delivered to the bone marrow as a preparative regimen before hematopoietic cell transplant while causing less side effects to normal organs than standard total body irradiation.

blood cell count
colony stimulating factor
chromosome abnormality
stem cell transplantation
serum pregnancy test
  • 0 views
  • 19 Feb, 2024
  • 1 location