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Found 11 clinical trials
Featured trial
Personalizing Sleep Interventions to Prevent Type 2 Diabetes in Community Dwelling Adults With Pre-Diabetes

This study will use continuous glucose monitoring and actigraphy to examine whether a personalized, daily sleep extension intervention improves glucose regulation for community dwelling, sleep-restricted adults with pre-diabetes. The randomized controlled trial will include 150 adults with pre-diabetes. Sleep extension and habitual sleep groups will complete daily sleep diaries and …

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  • 19 Feb, 2024
SGLT2 Inhibition in Older Obese Adults With Pre-diabetes

Inhibitors of the sodium-glucose co-transporter (SGLT2) are FDA-approved for the treatment of type 2 diabetes (T2DM). Their mechanism of action involves lowering of blood glucose concentration secondary to increased glucose excretion of glucose by the kidney. These drugs also improve body weight, blood pressure, and cardiac function. Based on these …

hemoglobin a1c
glycosylated hemoglobin
type 2 diabetes mellitus
diabetes
sglt2
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  • 19 Feb, 2024
Effect of 1 25-dihydroxyvitamin D3 Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons

The aim of this study is to assess the effects of 1,25(OH)2D3 on insulin secretion by the pancreas and glucose utilization by skeletal muscle as well as to determine the effects of 1,25(OH)2D3 on muscle strength in pre-diabetic persons

body mass index
fasting
insulin
serum glucose
prediabetic state
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  • 19 Feb, 2024
Incidence of Diabetes and Metabolic Disorders After TIPS in Cirrhotic Patients

Based on our retrospective data, TIPS induces in 30% of cirrhotic patients metabolic disorders associated with diabetes or pre-diabetes. The main objective is to measure the cumulative incidence of diabetes and pre-diabetes 6 months after TIPS insertion.

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  • 19 Feb, 2024
Study of the Factors Favoring the Transition From Prediabetes to Diabetes on Reunion Island.

It is important in Reunion island, in view of the specificities presented by our population, to understand the pre-diabetes / diabetes transition and the risk and protective factors.

hyperglycemia
glucose intolerance
stroke
prediabetic state
gestational diabetes
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  • 19 Feb, 2024
The Effect of Time-Restricted Eating in Cardiometabolic Health

The proposed studies will elucidate the cardiometabolic implications of TRE in people with obesity and prediabetes.

body mass index
hemoglobin a1c
glycosylated hemoglobin
plasma glucose
glucose intolerance
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  • 19 Feb, 2024
The Alberta NutrIMM Study - Nutrition and Immunity

Excess weight, nutrition, and blood sugar levels can all affect immune function, which in turn can affect participants risk for heart disease and type 2 diabetes (T2DM). It is not known how diet, blood sugar, and weight affect immune function. The purpose of the study is to look at how …

hemoglobin a1c
LDL Cholesterol
hyperglycemia
glycosylated hemoglobin
type 2 diabetes mellitus
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  • 19 Feb, 2024
Complex All-comers and Patients With Diabetes or Prediabetes Treated With Xience Sierra Everolimus-eluting Stents

Clinical outcome of patients with previously unknown (silent) diabetes and prediabetes is of increasing interest since the latter group has recently shown to be associated with a significant risk of adverse cardiovascular events after treatment with contemporary DES.

percutaneous coronary intervention
clinical syndromes
glucose intolerance
acute coronary syndrome
clinical syndrome
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  • 19 Feb, 2024
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies

The main aim of the study is to set up an observational cohort with NAFLD (Non-alcoholic fatty liver disease) at different stage of disease (from simple steatosis to cirrhosis and/or HCC-Hepatocellular carcinoma) and for comparative purpose a cohort of subjects with diabetes and/or obesity and/or other risk factors (i.e. psoriasis, …

liver disease
metabolic syndrome
hepatocellular carcinoma
hepatitis c
nonalcoholic fatty liver
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  • 19 Feb, 2024
Pilot Study - Cognition in Patients With Hypoglycemia Without Diabetes

The purpose of this study is to determine if there is a relationship between recurrent hypoglycemia (low blood sugar) and cognition (thinking) in individuals who have a history of hypoglycemia, but do not have pre-diabetes or diabetes. This study will analyze whether recurrent hypoglycemia is associated with differences in cognition …

cognitive assessment
hypoglycemia
neuroglycopenia
gastrointestinal surgery
dietary intervention
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  • 19 Feb, 2024