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Found 5 clinical trials
Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19

The HCW Prophylaxis (HCWP) Study, single, open and off label intervention study. Up to 350 participants will be assigned to group that takes HCQ or group that opts to not take study medication.

occupational exposure
pediatric
hydroxychloroquine
acute respiratory syndrome (sars)
covid-19
  • 0 views
  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

Doxapram is a respiratory stimulant that has been administered off-label to treat AOP. Doxapram, as add-on treatment, seems to be effective in treating AOP and to prevent invasive mechanical ventilation.

continuous positive airway pressure
lung disease
nervous
pulmonary disease
mechanical ventilation
  • 0 views
  • 19 Feb, 2024
A Study to Explore Personalized Treatment for Patients with Recurrent Gynecological Malignancies Based on MTB (RWS-MTB)

Attending physicians will determine the final treatment plan, integrating multidisciplinary recommendations with patient preferences, comorbidity considerations, drug toxicity assessments, insurance coverage for off-label medications, and the availability of investigational drug trials. This arm aims to observe and evaluate the clinical efficacy of personalized treatment plans developed through molecular tumor profiling …

  • 0 views
  • 17 Jan, 2025
Predictive Factors COVID-19 Patients

This is a monocentric retro-prospective observational study that will be conducted on all COVID19 positive patients hospitalized at the S. Gerardo Hospital in Monza.

acute respiratory syndrome (sars)
SARS
pneumonia
  • 0 views
  • 19 Feb, 2024
Off-label Use of Anti-cancer Drugs in Norway -a Prospective Cohort Study

Off-label drug use, where a marketed drug is used outside its approved indication, may allow early access to new and promising treatments.

off label use
antineoplastic agents
cancer diagnosis
cancer
  • 0 views
  • 19 Feb, 2024