multiple sclerosis Clinical Research Trials

Found 1294 clinical trials

Featured trial

Diffusion MRI for Head and Neck Cancer

D(t) and K(t) of tumors can vary substantially depending on t in the range of diffusion times (30-100 ms) typically used in clinical scan.

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29 Jul, 2025

Multi-country trial
Includes pre-screening
Phase 3
For adults
Recruiting in 100s
Interventional Study
all
Family Medicine
Recruiting

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

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04 Mar, 2025

Multi-country trial
Phase 3
For adults
Recruiting in 100s
Interventional Study
all
Recruiting

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

contraceptive use

teriflunomide

brain lesion

multiple sclerosis

urine test