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Found 2 clinical trials
Study to Evaluate the Pharmacokinetics (PK) of E7090 and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants
The primary purpose of the study is to evaluate the effects of mild and moderate hepatic impairment on PK of E7090 after a single dose administration.
body mass index
e7090
moderate hepatic impairment
moderate hepatic insufficiency
electrocardiogram
- 0 views
- 19 Feb, 2024
- 3 locations
The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics
This is a prospective, single-center, open-label, single-dose, Phase 1 study, to assess the effect of moderate hepatic impairment due to liver cirrhosis on the pharmacokinetics of aprocitentan (ACT-132577).
body mass index
kidney function tests
cirrhosis
serum pregnancy test
diastolic blood pressure
- 0 views
- 19 Feb, 2024
- 1 location