Found 7 clinical trials
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-sch nlein Purpura
The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with Henoch-schnlein purpura.
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- 19 Feb, 2024
- 1 location
InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK Cohort
Comparison of the effects of CYT107 vs Placebo administered IM at 10g/kg twice a week for two weeks on immune reconstitution of lymphopenic COVID-19 patients.
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- 19 Feb, 2024
- 1 location
InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection FR BL Cohort
Comparison of the effects of CYT107 vs Placebo administered IM at 10g/ kg twice a week for two weeks on immune reconstitution of lymphopenic COVID-19 patients.
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- 19 Feb, 2024
- 2 locations
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-na ve GBM Patients.
A multi-center, open-label, single-arm, phase I/II clinical study is designed to test the safety and immunogenicity of an investigational Dendritic and Glioma Cells Fusion vaccine given with IL-12 for treatment-nave patients after resection of glioblastoma.
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- 19 Feb, 2024
- 2 locations
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.
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- 19 Feb, 2024
- 1 location
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy
The use of anti-interleukin (IL)-6 therapy, including tocilizumab, in rheumatoid arthritis or giant cell arteritis, led to the improvement or even control of disease in some patients for whom no further therapeutic options were available. Nevertheless, the evaluation of the efficacy of these treatments are negatively impacted by the lack …
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- 19 Feb, 2024
- 1 location
Clinical Outcome of Anti-IL6 vs Anti-IL6 Corticosteroid Combination in Patients With SARS-CoV-2 Cytokine Release Syndrome
The cytokine storms mediated by over production of proinflammatory cytokines have been observed in a large population of critically ill patients infected with COVID-19. Patients diagnosed with cytokine storms progress to cardiovascular collapse, multiple organ dysfunction and death rapidly. Therefore, early identification, treatment and prevention of the cytokine storms are …
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- 19 Feb, 2024
- 1 location