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Found 4 clinical trials
Safety and Efficacy of Eliglustat With or Without Imiglucerase in Pediatric Patients With Gaucher Disease (GD) Type 1 and Type 3

Primary Objective: Evaluate the safety and pharmacokinetics of eliglustat in pediatric patients (2 to <18 years old). Secondary Objective: Evaluate the efficacy of eliglustat and quality of life in pediatric patients (2 to <18 years old).

thrombocytopenia
enzyme assay
eliglustat
cerezyme
osteopenia
  • 0 views
  • 19 Feb, 2024
  • 23 locations
מחקר להערכת הבטיחות, היעילות והאימונוגניות של חיסון mRNA לאקנה במבוגרים עם אקנה בינונית עד חמורה  

מטרת הניסוי היא להעריך את הבטיחות, היעילות והאימונוגניות של עד 3 זריקות תוך שריריות של חיסון mRNA לאקנה בעד שלוש רמות מינון במשתתפים בוגרים בגילאי 18 עד 45 עם אקנה בינונית עד חמורה.

thrombocytopenia
enzyme assay
eliglustat
cerezyme
osteopenia
  • 0 views
  • 10 Sep, 2025
  • 22 locations
Venglustat in Combination With Cerezyme in Adult and Pediatric Patients With Gaucher Disease Type 3

Primary Objectives: Part 1: Cohorts 1, 2 and 3 Evaluate cerebrospinal fluid (CSF) biomarkers in adult Gaucher disease (GD) Type 3 patients that distinguish GD3 from adult Gaucher disease Type 1 (GD1) patients. Screen adult and pediatric GD3 patients who qualify for treatment with venglustat in Parts 2 and 3. …

  • 0 views
  • 19 Feb, 2024
  • 7 locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

To characterize the Gaucher disease population. To evaluate the long-term effectiveness of imiglucerase and of eliglustat. Gaucher Pregnancy Sub-registry: The primary objective of this Sub-registry is to track pregnancy outcomes, including complications and infant growth, in all women with Gaucher disease during pregnancy, regardless of whether they receive disease-specific therapy.

imiglucerase
eliglustat
gaucher disease
deficiency
  • 0 views
  • 19 Feb, 2024
  • 221 locations