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Found 5 clinical trials
Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy

This is a Phase III, multicenter, randomized, open-label study designed to evaluate the efficacy, safety, and pharmacokinetics of atezolizumab given in combination with cabozantinib compared with docetaxel monotherapy in patients with metastatic NSCLC, with no sensitizing EGFR mutation or ALK translocation, who have progressed following treatment with platinum-containing chemotherapy and …

lung cancer
small cell lung cancer
hiv test
programmed cell death 1 ligand 1
hepatitis
  • 0 views
  • 19 Feb, 2024
Efficacy and Safety of Cabozantinib in Patients With Hepatocellular Carcinoma

This is an open-label, single-center, Phase II trial designed to estimate in terms of PFS the efficacy of cabozantinib, given as second- or third- line treatment in HCC patients that progress on or are intolerant to immune checkpoint inhibitors, including anti-PD-1 and anti-PD-L1 antibodies.

radiofrequency ablation
pd-l1
renal function test
hepatocellular carcinoma
hepatitis
  • 0 views
  • 19 Feb, 2024
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

This is a Phase 3, multi-center, randomized, open-label, controlled study designed to evaluate the safety and efficacy of cabozantinib given in combination with atezolizumab versus a second novel hormonal therapy (NHT) in men with metastatic castration-resistant prostate cancer (mCRPC) who have previously been treated with one, and only one, NHT …

endocrine therapy
darolutamide
bone disease
testosterone
castration-resistant prostate cancer
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  • 19 Feb, 2024
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

This phase I/II trial studies the side effects and best dose of cabozantinib when given with radiation therapy and how well it works in treating patients with sarcoma of the extremities. Cabozantinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

gilbert's syndrome
human chorionic gonadotropin
blood transfusion
colony-stimulating factors
sarcoma
  • 0 views
  • 19 Feb, 2024
A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET

A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroendocrine tumor (NET): The LOLA trial

warfarin
minor surgery
transient ischemic attack
electrolyte disturbances
24-hour urine protein test
  • 0 views
  • 19 Feb, 2024