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Found 1 clinical trials

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Phase 1
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Recruiting

The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

This is a prospective, single-center, open-label, single-dose, Phase 1 study, to assess the effect of moderate hepatic impairment due to liver cirrhosis on the pharmacokinetics of aprocitentan (ACT-132577).

moderate hepatic insufficiency

diastolic blood pressure

serum pregnancy test

renal function test

body mass index

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19 Feb, 2024

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