Found 1264 clinical trials
Immune Profiling of COVID19-patients Admitted to ICU
Throughout their ICU stay, multiple blood samples will be screened for leukocytes surface markers, leukocytes' production of certain molecules, and circulating cytokines/chemokines/checkpoint inhibitors. Their plasma/serum will be used as well for immune proteomics, metabolomics, and other serological tests. Such parameters can provide the more comprehensive status of COVID19-infected patients at …
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- 19 Feb, 2024
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Non Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols
The clinical diagnosis of the subject based on a combination of imaging, viral diagnostics and clinical assessment will be used as the reference standard. When this number hits 100 the study will be discontinued. In total no more than 500 subjects shall be sampled in this trial.
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- 19 Feb, 2024
- 1 location
Covid-19 Lockdown and Deviant Sexual Fantasies
The very characteristics of this confinement and of the disease (isolation, potential severity of the illness, being psychologically unprepared for such a circumstance) have a significant impact on one's psyche, like emotional disorders -anxiety/depression-, difficulties when returning to normal life, vicarious traumas Confinement is paradoxical in as although well-intended to …
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- 19 Feb, 2024
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GFAP Auto-immunity : a French Cohort Study
Glial fibrillary acidic protein (GFAP)-Immunoglobulin G (IgG) have recently been described as a biomarker of a novel inflammatory central nervous system (CNS) disorder, termed autoimmune GFAP astrocytopathy. Thus far, four major clinical series have been published (two from Mayo Clinic USA, one from Italy and one from China).
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- 19 Feb, 2024
- 1 location
Development of a Simple Fast and Portable Recombinase Aided Amplification Assay for 2019-nCoV
In parallel, The investigators also used the commercial RT-qPCR assay kit for 2019-nCoV as a reference.
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- 19 Feb, 2024
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Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.
The evaluation of the tumor microcirculation by Doppler ultrasound has been used in many tumors and defined as vascularity index (VI). The power Doppler sonography has many advantages over color Doppler ultrasound in studying the vascularity.
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- 19 Feb, 2024
- 1 location
Biomarkers in Rheumatoid Arthritis Treated With Anti-interleukin-6 Therapy
Indeed, usual inflammatory biomarkers used during the follow-up of these patients to detect persistent disease activity or intercurrent infection, such as C-reactive protein, fibrinogen and procalcitonin, are dependant on IL-6. Thse usual biomarkers cannot therefore be reliably used during anti-IL-6 therapy.
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- 19 Feb, 2024
- 1 location
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects
A sterile cotton swab may be rubbed over their skin or inside the cheek or nose to collect cells. If participants have samples collected as part of their regular medical care, their doctor may be asked to send parts of the samples that otherwise would be thrown away. These samples …
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- 19 Feb, 2024
- 1 location
Assessment of Motor Reserve in the Preclinical Stages of Dementia
Although cognitive alterations have traditionally been the main focus of investigation, growing evidence suggests that motor changes may also emerge during the early stages of cognitive decline and may represent potential preclinical indicators of disease.In this context, the concept of motor reserve has emerged as a construct of increasing interest, …
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- 10 Jun, 2026
- 1 location
Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative Therapies
These characteristics therefore allow them to summarize the clinical spectra of cancers, but also to be models for studying tumor progression as has been done with organoids for colorectal cancer. They are also very close morphologically and genetically to the tumor from which they derive.Finally, clinical trials are underway to …
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- 19 Feb, 2024
- 1 location