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Found 1041 clinical trials
COVID - AirPollution

In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of …

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  • 19 Feb, 2024
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

agitation
behavioral disturbances
postoperative pain
tonsillectomy
adenoidectomy
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  • 19 Feb, 2024
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.

hypertension
placenta
mass spectrometry
microbiota
diabetes
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  • 19 Feb, 2024
Retention and Durability of the Anterior Zirconia Wing Bridge

The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …

dental filling
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  • 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".

localized disease
metastasis
adriamycin
metastatic osteosarcoma
adjuvant therapy
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  • 19 Feb, 2024
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis

However, the stenosis severity is not closely corresponding with the hemodynamic significance in coronary arteries. As a result, fractional flow reserve (FFR) with pressure wire measurement was introduced to functionally assess the coronary stenosis.

stenotic
heart disease
hyperemia
ischemia
coronary ct
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  • 19 Feb, 2024
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

carcinoma
carcinoma in situ
stage iv non-small cell lung cancer
cancer
carcinoma of the cervix
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  • 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

It is hoped that soon we will be able to monitor cancer by analysing a patient's blood samples, thus reducing the need for biopsies. As blood tests could be taken more frequently, signs that patients are becoming resistant to treatments could be picked up sooner. As well as monitoring biomarkers, …

advanced melanoma
cancer
metastatic melanoma
cancer treatment
metastatic malignant melanoma
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  • 19 Feb, 2024
Validity and Reliability of the Turkish Version of the Sydney Swallow Questionnaire

Purpose of the study is the validity and reliability of the Turkish version of the Sydney Swallow Questionnaire (SSQ-T), so that it would be used as an assessment tool for Turkish dysphagia patients. Despite being translated and validated in many languages, there is no validated Turkish version of SSQ to …

dysphagia
oropharyngeal
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  • 19 Feb, 2024
Impact of Sinus Surgery on Individuals With Cystic Fibrosis

Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

rhinosinusitis
fibrosis
sweat test
medical therapy
sinus surgery
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  • 19 Feb, 2024