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Found 1352 clinical trials
EAS Familial Hypercholesterolaemia Studies Collaboration

Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C results in a substantially increased risk of (premature) cardiovascular disease as compared to the general population. Although FH adverse cardiovascular outcomes are potentially preventable through early …

early identification
genetic disorder
lipoprotein cholesterol
hypercholesterolemia
cardiovascular disease
  • 0 views
  • 19 Feb, 2024
Gene Mutation Spectrum of Malignant Hyperthermia in China

The MH bioinformatics database will be established to find the pathogenic gene and mutation site of MH in Chinese. Based on the bioinformatics database, the genetic law of MH family will be studied.

  • 0 views
  • 19 Feb, 2024
Evaluation of Cognitive State Using Neurosteer EEG System

EEG recordings will be analyzed using proprietary computational analyses.

mini-mental state examination
seizure
cognitive assessment
  • 0 views
  • 19 Feb, 2024
Giessen Pulmonary Hypertension in Lung Cancer Registry

All information will be generated from the regular guidelines based course of treatment and there will be no interventions. This study will serve as a prospective register for all lung cancer patients treated at the university hospital Giessen.

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  • 19 Feb, 2024
GSD IX Natural History Study

Participant's medical charts will be continually reviewed for the duration of the study. If a liver, muscle or skin biopsy sample has been collected, a piece of the sample may be requested and stored for research purposes.

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  • 19 Feb, 2024
Prospective Evaluation of Performance of Disposable Elevator Cap Duodenoscope During ERCP in Clinical Practice

More specifically in the quality metrics sector we will be able to see what is already in place and steps we will undertake that will be beneficial for physicians.

endoscopic retrograde cholangiopancreatography
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  • 19 Feb, 2024
Analysis of the Inflammatory Response and the Development of Humoral and Cellular Immunity in Patients With COVID-19

Finally, an epidemiological analysis of the patients will be carried out.

inflammatory response
cytokines
antibody titer
SARS
covid-19
  • 0 views
  • 19 Feb, 2024
Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis

COVID-19 patients with severity criteria will be compared to patients with mild disease managed at home. A deep phenotyping related to the symptoms of the disease as well as biosampling allowing for laboratory-based and computational analytics will be performed.

SARS
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
A Study of the Effectiveness of Venetoclax Tablets in Adult Acute Myeloid Leukemia Participants Ineligible for Standard Induction Therapy in Russian Federation

Adult participants with a diagnosis of AML who are ineligible for standard induction therapy will be enrolled. Around 50 participants will be enrolled in the study in approximately 15 sites in Russian Federation. Participants will receive venetoclax tablets to be taken by mouth daily according to the approved local label.

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  • 19 Feb, 2024
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy

The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be elaborated to reduce the rate of complications in the early and long-term postoperative period in patients with ischemic cardiomyopathy.

myocardial infarction
cardiomyopathy
cabg
coronary bypass
stenosis
  • 0 views
  • 19 Feb, 2024