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Found 1009 clinical trials
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.

hypertension
diabetes
mass spectrometry
microbiota
placenta
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  • 19 Feb, 2024
Retention and Durability of the Anterior Zirconia Wing Bridge

The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …

dental filling
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  • 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".

metastatic osteosarcoma
metastasis
tumor necrosis
adjuvant therapy
p-glycoprotein
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  • 19 Feb, 2024
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis

However, the stenosis severity is not closely corresponding with the hemodynamic significance in coronary arteries. As a result, fractional flow reserve (FFR) with pressure wire measurement was introduced to functionally assess the coronary stenosis.

coronary ct
coronary artery stenosis
ischemia
stenosis
quantitative coronary angiography
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  • 19 Feb, 2024
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

carcinoma of the cervix
carcinoma in situ
stage iii non-small cell lung cancer
chemoradiotherapy
non-melanoma skin cancer
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  • 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

It is hoped that soon we will be able to monitor cancer by analysing a patient's blood samples, thus reducing the need for biopsies. As blood tests could be taken more frequently, signs that patients are becoming resistant to treatments could be picked up sooner. As well as monitoring biomarkers, …

metastatic malignant melanoma
blood test
cancer
cancer treatment
advanced melanoma
  • 0 views
  • 19 Feb, 2024
Validity and Reliability of the Turkish Version of the Sydney Swallow Questionnaire

Purpose of the study is the validity and reliability of the Turkish version of the Sydney Swallow Questionnaire (SSQ-T), so that it would be used as an assessment tool for Turkish dysphagia patients. Despite being translated and validated in many languages, there is no validated Turkish version of SSQ to …

oropharyngeal
dysphagia
  • 0 views
  • 19 Feb, 2024
Impact of Sinus Surgery on Individuals With Cystic Fibrosis

Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

sweat chloride test
sinusitis
sinus surgery
sweat chloride
cystic fibrosis
  • 0 views
  • 19 Feb, 2024
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms

Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. Create algorithms to monitor and track changes to COVID19-like signs and symptoms for developing a better care and isolation strategies for COVID-19 pandemic.

cough
dyspnea
covid-19
confusion
fever
  • 0 views
  • 19 Feb, 2024
Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers

Evaluating antibody response to high-dose seasonal influenza vaccine may serve as a basis for vaccine recommendations in patients with myeloid malignancies and provide insights into the status of the immune system in these patients.

myeloid neoplasm
antibody response
influenza
influenza vaccination
myeloid malignancy
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  • 19 Feb, 2024