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Found 1009 clinical trials
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency

To date, the investigators lack characterization of, the burden of, and the systemic progression of disease in ENPP1 deficiency and ABCC6 deficiency from a patient and/or parent perspective. This study aims to document this characterization, progression as well as the burden of disease. Link to the study registration-

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  • 19 Feb, 2024
Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis

Signs of heart failure (dyspnea, reduced resilience, tendency to edema), thoracic pain, palpitations / arrhythmias / syncope, as well as (potentially) lethal clinical conditions in the sense of a cardiogenic shock or sudden cardiac death can be found. In 2015, the European Society of Cardiology (ESC) gave a IIa recommendation …

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  • 19 Feb, 2024
Accuracy of Cardiac Acoustic Biomarkers Recorded by the Wearable Cardioverter Defibrillator

Evaluate data accuracy of cardiac acoustic biomarkers (CABs) recorded by the Wearable Cardioverter Defibrillator (WCD) as compared to the AUDICOR AM acoustic cardiography recorder.

cardiomyopathy
ejection fraction
  • 0 views
  • 19 Feb, 2024
Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

The surveys will analyze the impact of the patients' treatment choices, as well as patient adherence, in a rural setting.

cancer
proctectomy
rectal cancer
  • 0 views
  • 19 Feb, 2024
Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia

Furthermore, the investigators want to investigate whether there is an association between subclinical epileptic activity and the cerebral blood flow as measured with functional MRI.

depression
neuropsychological assessment
lewy body dementia
psychiatric disorder
neuropsychological test
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  • 19 Feb, 2024
Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

decompensated heart failure
adhf
hemodynamic measurements
heart failure
acute decompensated heart failure
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  • 19 Feb, 2024
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours

This is necessary for two reasons: (1) the current literature on ADHD impairment and functioning is concentrated within elementary school children; and (2) studies of intervention effectiveness are typically concentrated during the school day. This current state of the literature ignores the obvious - as ADHD is a chronic disorder, …

chronic disease
psychosis
psychiatric disorder
autism
pervasive developmental disorder
  • 0 views
  • 19 Feb, 2024
Development and Analysis of a Stool Bank for Cancer Patients

Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are limited due to differences between mouse and human physiology and immunology, as well as the inherent differences in gut microbial populations between the two mammalian organisms. Therefore, samples obtained …

immunotherapies
cancer immunotherapy
cancer treatment
pembrolizumab
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  • 19 Feb, 2024
COVID - AirPollution

In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of …

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  • 19 Feb, 2024
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

pediatric
pain assessment
behavioral disturbances
agitation
postoperative pain
  • 0 views
  • 19 Feb, 2024