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Found 89 clinical trials
Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma

The investigators propose a phase II randomized-controlled study on using durvalumab in combination with induction chemotherapy followed by concurrent chemoradiation and adjuvant durvalumab, compared to induction chemotherapy followed by concurrent chemoradiation for previously untreated locoregionally advanced stage III to IVA NPC. In parallel, the investigators will also perform collateral tumor …

hysterectomy
pet/ct scan
cisplatin
immunosuppressive agents
intra-articular injection
  • 0 views
  • 19 Feb, 2024
A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors

In this study, patients with advanced solid tumors will undergo [18F]F AraG PET/CT imaging to assess for changes in tracer uptake following treatment with CkIT.

  • 0 views
  • 19 Feb, 2024
L-TIL in Patients With Malignancy Resistance to Anti-PD-1 Therapy

Safety and effectiveness of liquid tumor infiltrating lymphocytes in patients with advanced malignant tumors who have failed to anti-PD-1 therapy

measurable disease
cancer
blood pregnancy test
  • 0 views
  • 19 Feb, 2024
Characterization of Methylation Patterns in Cancer and Non-Cancer cfDNA

Nucleix EpiCheck tests analyzes the methylation pattern in a panel of DNA methylation biomarkers and determines whether this pattern is consistent with cancer under test or with non-cancer tissue. This study is being performed as part of the development process of the Pan Cancer EpiCheck test which includes the identification …

cancer
cfdna
  • 0 views
  • 19 Feb, 2024
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors

This study uses questionnaires to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted health-related quality of life (HRQOL) and other areas such as COVID-19-specific psychological distress, disruptions to health care, finances and social interactions in cancer patients. The coronavirus disease 2019 …

malignant solid neoplasm
cancer
solid neoplasm
coronavirus infection
psychological distress
  • 0 views
  • 19 Feb, 2024
NCI COVID-19 in Cancer Patients NCCAPS Study

This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects …

oropharyngeal
hematopoietic and lymphoid cell neoplasm
viral test
cancer therapy
biospecimen collection
  • 0 views
  • 19 Feb, 2024
  • 1 location
Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants

To determine the optimal EGFR TKIs treatment strategies for lung adenocarcinoma harboring EGFR exon 19 deletion variants

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  • 19 Feb, 2024
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Eligibility People starting at age 3 and older who have or are suspected of having NENs and are enrolled in protocol 19C0016, Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors Design Participants will be screened with questions about their medical history. This may be …

positron emission tomography
chromogranin a
5-hydroxyindoleacetic acid
dotatate
neuron-specific enolase
  • 0 views
  • 19 Feb, 2024
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Background Adrenocortical cancer (ACC) is a rare tumor. The prognosis is very poor for people with advanced stages of ACC. Some people may live with ACC for years; others live for just months. Treatment options for ACC often do not work well. Researchers want to study the clinical course of …

blood tests
adrenal
adrenocortical carcinoma
cancer
solid tumors
  • 0 views
  • 19 Feb, 2024