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Found 219 clinical trials
Asian Diabetes Outcomes Prevention Trial

The aim of this study is to identify patients with DM at high risk of CVD using elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (>125pg/mL), and (2) intensify therapy using renin-angiotensin system (RAS) antagonists, beta-blockers and sodium glucose co-transporter-2 inhibitors (SGLT2i) for primary prevention of cardiovascular events in this high-risk …

nesiritide
myocardial infarction
angiotensin
coronary revascularization
beta blocker
  • 0 views
  • 19 Feb, 2024
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease

Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease

heart disease
intravascular ultrasound
arterial disease
angiography
stenosis
  • 2 views
  • 19 Feb, 2024
The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty

This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery. Half of the participants will be randomized into the exercise group, while the other half will be randomized into the control group.

  • 0 views
  • 19 Feb, 2024
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives:

<ul>
  • Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B
  • Dose Expansion Part B: To assess …

    autologous hematopoietic stem cell transplant
    multiple myeloma
    daratumumab
    lenalidomide
    immunotherapeutic agent
    • 0 views
    • 19 Feb, 2024
    • 8 locations
    Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

    This research study involves the following investigational drugs:

    <ul>
  • Ipatasertib
  • Atezolizumab
  • ul>

    granulocyte colony stimulating factor
    lumpectomy
    axillary lymph node dissection
    serum bilirubin level
    lymphadenectomy
    • 0 views
    • 19 Feb, 2024
    Cisplatin+Pembrolizumab+RT in Vulvar Cancer

    This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma.

    This research study involves the following:

    <ul>
  • Cisplatin (standard of care drug)
  • Pembrolizumab (investigational drug)
  • Radiation Therapy (standard …

    radical vulvectomy
    recurrent disease
    neutrophil count
    endocrine therapy
    carcinoma
    • 0 views
    • 19 Feb, 2024
    Ibrutinib + Venetoclax in Untreated WM

    The names of the study drugs involved in this study are:

    <ul>
  • Venetoclax
  • ibrutinib
  • ul>

    myd88 gene mutation
    waldenstrom's macroglobulinemia
    serum pregnancy test
    ibrutinib
    neutrophil count
    • 0 views
    • 19 Feb, 2024
    Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

    The names of the study interventions involved in this study are:

    <ul>
  • Sacituzumab govitecan (IMMU-132)
  • Pembrolizumab (Keytruda; MK-3475)
  • ul>

    progesterone
    periodic abstinence
    neuropathy
    cns disease
    neutrophil count
    • 8 views
    • 19 Feb, 2024
    Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

    The name of the study intervention involved in this study is:

    <ul>
  • Implantation of a MR-guided microdevice
  • ul>

    prostatectomy
    carcinoma
    neutrophil count
    • 2 views
    • 19 Feb, 2024
    Genetic Testing for All Breast Cancer Patients (GET FACTS)

    The names of the study methods involved in this trial are/is:

    <ul>
  • Quantitative genetic counseling (discussion is guided by tables and graphs)
  • Standard genetic counseling
  • ul>

    breast carcinoma
    genetic testing
    cancer
    genetic counseling
    cancer diagnosis
    • 0 views
    • 19 Feb, 2024