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Found 1317 clinical trials
Diagnostic Performance of a New Method for the Echocardiographic Assessment of Coronary Arteries Abnormalities

Coronary artery anomalies (CAA) are a rare congenital condition, accounting abnormalities of origin, course, destination, size, and number of the coronary vessels. In normal hearts, the coronary arteries, the left and right coronary arteries (LCA and RCA, respectively) originate from the two facing aortic sinuses of Valsalva, so-called left and …

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  • 19 Feb, 2024
Assesment of Multiomics Profiles in Health and Disease.

This study will determine reference genomic, transcriptomic, proteomic and metabolomic profiles in Czech population and will evaluate its correlation with the disease phenotype.

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  • 19 Feb, 2024
Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence

The purpose of this research is to prospectively test and validate the single-lead Low EF algorithm in outpatients in order to test the performance of a single-lead ECG based algorithm to identify people with decreased left ventricular EF.

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  • 19 Feb, 2024
Prediction of Therapeutic Response of Apatinib in Recurrent Gliomas

Apatinib, also known as YN968D1, is a small-molecule tyrosine kinase inhibitor (TKI) that selectively binds to and inhibits vascular endothelial growth factor receptor 2 (VEGFR-2). This study aims to collect clinical, radiological and histopathology imaging including detailed radiological data, survival data, clinical parameters, molecular pathology and images of HE slices …

growth factor
postoperative complication
vegf
tyrosine
neutrophil count
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  • 19 Feb, 2024
A 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health

This is a 48-month observational, prospective, multicentre study. The overall aim of the study is to evaluate the long-term effectiveness of Elocta treatment on joint health in patients treated prophylactically with Elocta in a real-world setting.

hemophilia
antihemophilic factor
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  • 19 Feb, 2024
EAS Familial Hypercholesterolaemia Studies Collaboration

Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C results in a substantially increased risk of (premature) cardiovascular disease as compared to the general population. Although FH adverse cardiovascular outcomes are potentially preventable through early …

early detection
premature
cardiovascular disease
hypercholesterolemia
genetic disorder
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  • 19 Feb, 2024
Gene Mutation Spectrum of Malignant Hyperthermia in China

The MH bioinformatics database will be established to find the pathogenic gene and mutation site of MH in Chinese. Based on the bioinformatics database, the genetic law of MH family will be studied.

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  • 19 Feb, 2024
Evaluation of Cognitive State Using Neurosteer EEG System

EEG recordings will be analyzed using proprietary computational analyses.

seizure
cognitive assessment
mini-mental state examination
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  • 19 Feb, 2024
Giessen Pulmonary Hypertension in Lung Cancer Registry

All information will be generated from the regular guidelines based course of treatment and there will be no interventions. This study will serve as a prospective register for all lung cancer patients treated at the university hospital Giessen.

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  • 19 Feb, 2024
GSD IX Natural History Study

Participant's medical charts will be continually reviewed for the duration of the study. If a liver, muscle or skin biopsy sample has been collected, a piece of the sample may be requested and stored for research purposes.

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  • 19 Feb, 2024