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Found 2,825 clinical trials

S Stephen Baldassarri, M.D.

Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-nave smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

21-55 years All Phase N/A
A April Fenner, RN

Evaluation of Stool Microbiome Using HyGIeaCare Prep

Stool samples will be collected before and during the HyGIeaCare procedure and the samples will be sent for microbiome evaluation.

18-80 years All Phase N/A
R Russ Smiley

A Safety and Tolerability Study of 10XB-101 Injections in Adult Subjects With Extra Fat Under the Chin ("Double Chin")

The purpose of this research study is to find out more about an investigational drug, 10XB-101, for people with fat under their chin which they would like to remove. The Sponsor of this study thinks there may be a chance this drug could be used to dissolve, or "melt" this …

18-65 years All Phase 2
K Kulveer Mankia

Abatacept in Individuals Who aRe Considered At Risk of Developing Inflammatory Arthritis

Phase II, single-centre, open label, two parallel arm cohort randomised controlled trial (RCT) testing abatacept in a population of anti-CCP Ab positive individuals at moderate to high risk of developing IA according to a published risk score, already followed in the observational study 'CCP: Next Generation'

18 years and older All Phase 2
T Thomas Schnelldorfer, MD, PhD

Efficacy of Near-Infrared Vein Imaging for Difficult IV Placement

The objective of this project is to define the effectiveness and therefore the role of NIR vein finders in adult patients with difficult peripheral venous access. The specific objective of the proposed randomized controlled trial is to test the clinical success rate of placing peripheral venous catheters in 'difficult' access …

15 years and older All Phase N/A
A Anke Claes, PhD student

Which Factors Influence the Outcome After Anatomical and Reverse Shoulder Arthroplasty?

The aim of this study is to investigate pre-, intra- and post-operative factors that influence post-operative outcome (shoulder pain, shoulder function and quality of life) after shoulder arthroplasty.

18 years and older All Phase N/A
A Albert Moore, MD

Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery Analgesia

This study is a Randomized Control Trial comparing the Erector Spinae Plane Block with intrathecal morphine for post cesarean delivery analgesia.

18-45 years Female Phase 3
M Mike Grady

Customer Outcomes & Value Experiencing A New Monitoring Technology

To investigate whether novel insight features in new Blood Glucose Monitoring System (BGMs) can improve glycemic control.

16 years and older All Phase N/A
T Thomas Lehman, MD

Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

18 years and older All Phase N/A
S Steffany Lim

Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

18 years and older All Phase 1/2

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