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Found 792 clinical trials
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

advanced breast cancer
breast cancer staging
carcinoma
potassium
  • 0 views
  • 19 Feb, 2024
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

cancer
chemoradiotherapy
head and neck cancer
lymphadenopathy
external beam radiotherapy
  • 0 views
  • 19 Feb, 2024
Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

A prospective, single-arm, multicenter, exploratory study to evaluate the efficacy and safety of D-CLAG regimen in the treatment of relapsed or refractory acute myeloid leukemia

cytarabine
clag regimen
granulocyte colony stimulating factor
acute leukemia
refractory acute myeloid leukemia (aml)
  • 0 views
  • 19 Feb, 2024
Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients

Deep brain stimulation of the NST is effective for cardinal motor signs in patients with idiopathic Parkinson's disease (IPD), its effects on gait disturbances, especially freezing of gait-FOG, and falls are variable from one patient to another, in part depending on the location of the NST-stimulating contact. The ability to …

dopa
tubal ligation
brain stimulation
parkinson's disease
estrogen
  • 0 views
  • 19 Feb, 2024
Personalized Performance Optimization Platform (P-POP)

Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance. Crews will have to operate under conditions of high workload, reduced sleep and circadian dysregulation, limited sensory stimulation, confinement and extended separation from family and friends, …

Accepts healthy volunteers
  • 0 views
  • 21 May, 2025
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

levodopa
brain stimulation
parkinson's disease
dyskinesia
  • 6 views
  • 19 Feb, 2024
  • 15 locations
Sleepiness in Parkinson's Patients With Continuous Dopaminergic Delivery Device or Deep Brain Stimulation

Sleepiness is frequent in parkinsonian patients, increasing with the duration of disease. By patients with motor fluctuations, continuous dopaminergic delivery devices or deep brain stimulation are justified to improve the motor prognosis. Antiparkinsonian treatments, especially dopaminergic agonists, may worsen the sleepiness and thus affect the quality of life. We aimed …

dopamine agonists
brain stimulation
parkinson's disease
antiparkinsonian agents
somnolence
  • 0 views
  • 19 Feb, 2024
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

transcutaneous electrical nerve stimulation
cesarean section
analgesia
toxic epidermal necrolysis
postoperative pain
  • 0 views
  • 19 Feb, 2024
SCS Stimulation Clamp to Assess Impact of Stimulation on Glucose Metabolism

In 1967 spinal cord stimulation (SCS) for the treatment of chronic neuropathic pain was established. Today various pain syndromes like the failed back surgery syndrome (FBSS), the complex regional pain syndrome (CRPS), ischemic pain or phantom limb pain are treated with SCS. The development of this technique based on the …

  • 0 views
  • 19 Feb, 2024
Previously Implanted Pudendal Nerve Stimulation

This study seeks to examine the response of the bladder to different pudendal nerve stimulation frequencies, by studying patients who have been previously-implanted with pudendal nerve neurostimulators.

  • 0 views
  • 19 Feb, 2024