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Found 793 clinical trials
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

breast cancer staging
potassium
advanced breast cancer
carcinoma
  • 0 views
  • 19 Feb, 2024
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer

The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.

neck cancer
external beam radiotherapy
squamous cell carcinoma
head and neck cancer
chemoradiotherapy
  • 0 views
  • 19 Feb, 2024
Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)

A prospective, single-arm, multicenter, exploratory study to evaluate the efficacy and safety of D-CLAG regimen in the treatment of relapsed or refractory acute myeloid leukemia

cladribine
myeloid leukemia
nephropathy
idarubicin
ejection fraction
  • 0 views
  • 19 Feb, 2024
Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients

Deep brain stimulation of the NST is effective for cardinal motor signs in patients with idiopathic Parkinson's disease (IPD), its effects on gait disturbances, especially freezing of gait-FOG, and falls are variable from one patient to another, in part depending on the location of the NST-stimulating contact. The ability to …

parkinson's disease
estrogen
brain stimulation
dopa
tubal ligation
  • 0 views
  • 19 Feb, 2024
Personalized Performance Optimization Platform (P-POP)

Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance. Crews will have to operate under conditions of high workload, reduced sleep and circadian dysregulation, limited sensory stimulation, confinement and extended separation from family and friends, …

Accepts healthy volunteers
  • 0 views
  • 21 May, 2025
Deep Brain Stimulation (DBS) for Parkinson's Disease International Study  

To gather data on DBS Therapy effectiveness in different geographic populations.

brain stimulation
levodopa
parkinson's disease
dyskinesia
  • 6 views
  • 19 Feb, 2024
  • 15 locations
Sleepiness in Parkinson's Patients With Continuous Dopaminergic Delivery Device or Deep Brain Stimulation

Sleepiness is frequent in parkinsonian patients, increasing with the duration of disease. By patients with motor fluctuations, continuous dopaminergic delivery devices or deep brain stimulation are justified to improve the motor prognosis. Antiparkinsonian treatments, especially dopaminergic agonists, may worsen the sleepiness and thus affect the quality of life. We aimed …

parkinson's disease
antiparkinsonian agents
dopamine agonists
somnolence
brain stimulation
  • 0 views
  • 19 Feb, 2024
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

analgesia
transcutaneous electrical nerve stimulation
toxic epidermal necrolysis
cesarean section
postoperative pain
  • 0 views
  • 19 Feb, 2024
SCS Stimulation Clamp to Assess Impact of Stimulation on Glucose Metabolism

In 1967 spinal cord stimulation (SCS) for the treatment of chronic neuropathic pain was established. Today various pain syndromes like the failed back surgery syndrome (FBSS), the complex regional pain syndrome (CRPS), ischemic pain or phantom limb pain are treated with SCS. The development of this technique based on the …

  • 0 views
  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

Restrictive invasive ventilation is therefore advocated nowadays in preterm infants. Doxapram is a respiratory stimulant that has been administered off-label to treat AOP. Doxapram, as add-on treatment, seems to be effective in treating AOP and to prevent invasive mechanical ventilation.

off-label
continuous positive airway pressure
lung disease
nervous
doxapram
  • 0 views
  • 19 Feb, 2024