Oxaliplatin Adjuvant Chemotherapy After Curative Resection of Primary Colon Cancer

According to general medical guidelines, adjuvant chemotherapy is used after curative resection of high-risk stage II or III primary colon cancer. However, there exist limitations using clinical trial data acquired from highly selected subjects in a controlled environment. For example, patients aged over 70 years old were in many cases …

Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19.

The primary objective of this study is to establish differences in susceptibility to SARS CoV-2 infection among health care workers (HCW) highly exposed to patients with COVID-19 diagnosis. To ascertain this issue, we evaluated:

Understanding the Transition from Normal Melanocytes to Nevus to Melanoma (NevustoMel)  

Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children

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The samples will be analyzed using a technique called metabolomics to identify biomarker candidates with diagnostic and/or prognostic potential.

Mechanisms of Post-Bariatric Hypoglycemia

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We will test the hypothesis that counterregulatory hormone responses are impaired in individuals with PBH, and that differences in the intestinal bacteria (microbiome) may contribute to this condition.

Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs

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The secondary objective is to assess outcome and identify risk factors of ICUCA occurrence among patients admitted for COVID-19.

Interest of a Period of Fasting Before Extubation in Resuscitation Patients

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Enteral nutrition is commonly discontinued to manage extubation, but it is not systematic. Discontinuation leads to a decrease in caloric intake.

Evaluation of the Satisfaction of Patients Coming "on Foot" in the Operating Room

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Currently, in the investigator's various institutions, several modes of transport to the operating theatres coexist. The purpose of this observational study is to evaluate this optimization of perioperative management "3D mode", in particular the mode of transport.

ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Post-authorization, observational, multicenter and prospective study in patients between 2 and 30 years old diagnosed with non-metastatic high-grade osteosarcoma of the extremities. All patients included in the study will receive the initial neoadjuvant treatment prescribed by the doctor of each center, according to standard practice (involving methotrexate, cisplatin, and adriamycin). …

Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …