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Found 681 clinical trials
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A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma

This is a single-arm, open-label, multicenter, Phase 1 study evaluating the safety and efficacy of CTX130 in subjects with relapsed or refractory renal cell carcinoma.

karnofsky performance status
renal cell carcinoma
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 2 locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

HER2
measurable disease
solid tumour
gene amplification
pembrolizumab
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

small cell lung cancer
advanced urothelial cancer
braf inhibitor
melanoma
squamous cell carcinoma of the skin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

This phase II trial studies how well lenvatinib and pembrolizumab before surgery work in treating patients with kidney cancer that has spread from its original site of growth to nearby tissues or lymph nodes but has not spread to other places in the body (non-metastatic). Lenvatinib may stop the growth …

liver metastasis
chorionic gonadotropin
beta human chorionic gonadotropin
metastatic renal cell carcinoma
international normalized ratio
  • 8 views
  • 19 Feb, 2024
  • 1 location