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Found 6792 clinical trials
Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes

This study will evaluate the effects of 3 intra-nodal injections of GAD-alum (Diamyd), together with oral vitamin D supplementation. Safety and feasibility of the treatment will be evaluated and also effects on the immune system and on the preservation of endogenous insulin production.

metformin
vitamin d supplementation
vitamins
vitamin d
diabetes
  • 0 views
  • 19 Feb, 2024
Cardiometabolic Effects of Rapid Glucose Excursion

The effects of rapid glucose excursions, induced by intravenous bolus application of glucose in healthy probands, on cardiometabolic and inflammatory parameters will be investigated

  • 0 views
  • 19 Feb, 2024
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

diabetes
teplizumab
type 1 diabetes mellitus
  • 0 views
  • 19 Feb, 2024
Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

The objective of this early feasibility study is to evaluate the safety and performance of intravascular hepatic denervation using the Metavention Integrated Radio Frequency Denervation System (iRF System) to improve glycemic control in type 2 diabetes subjects.

nash
hypertension
hypertension medication
fatty liver
liver disease
  • 0 views
  • 19 Feb, 2024
Internet Intervention for Diabetes Distress.

This study is designed to investigate the potential effectiveness of an internet-delivered intervention for diabetes distress in patients with type 2 diabetes.

Accepts healthy volunteers
  • 0 views
  • 20 Jun, 2025
  • 19 locations
Scripps Digital Diabetes: Cloud-Based Continuous Glucose Monitoring (CB CGM)

The work proposed pushes the limits of these challenges by providing evidence, identified by a team-based approach to glucose management in an underserved and understudied population supplementing prior data designed to improve outcomes among high-risk patients with type 2 diabetes (T2D) and related cardio metabolic conditions. The proposed intervention is …

hypoglycemia
hyperglycemia
poor glycaemic control
cardiovascular complication
hypoglycaemic episode
  • 0 views
  • 19 Feb, 2024
SGLT2 Inhibition in Older Obese Adults With Pre-diabetes

Inhibitors of the sodium-glucose co-transporter (SGLT2) are FDA-approved for the treatment of type 2 diabetes (T2DM). Their mechanism of action involves lowering of blood glucose concentration secondary to increased glucose excretion of glucose by the kidney.

body mass index
diabetes
hemoglobin a1c
glycosylated hemoglobin
sglt2
  • 0 views
  • 19 Feb, 2024
UPENN Case Test Trial 2 (Do Not Make Any Changes)

UPENN Case Test Trial 2 (Do Not Make Any Changes)

  • 0 views
  • 02 May, 2025
  • 1 location
UPENN Case Test Trial 4 (Do Not Make Any Changes)

UPENN Case Test Trial 4 (Do Not Make Any Changes)

  • 0 views
  • 02 May, 2025
  • 1 location
UPENN Case Test Trial 5 (Do Not Make Any Changes)

UPENN Case Test Trial 5 (Do Not Make Any Changes)

  • 0 views
  • 12 Jun, 2025