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Found 688 clinical trials
Prediction Model fo Screening and Diagnosis of Prostate Cancer in PSA Gray Zone Based on Serum PHI Combined With TPV

Prostate cancer (PCa) is a high incidence tumor of elderly men. In recent years, its incidence has rapidly increased in China. Serological examination of prostate-specific antigen (PSA) is particularly important in the early diagnosis of PCa, but its specificity is lower in gray areas with PSA between 4-10 ng / …

biopsy of prostate
prostate health index
cancer diagnosis
transrectal ultrasound
prostate specific antigen
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  • 19 Feb, 2024
Identify the Obstacles to Early Diagnosis of Cancer in Patients Over 75 Years Old on an Outpatient Basis

Delayed treatment causes a decrease in survival and quality of life. Cancer can be discovered suddenly: for example, occlusion with peritonitis in case of a stenosing colonic tumor, leading to urgent management.

breast cancer
cancer care
advanced cancer
early detection
early diagnosis
  • 0 views
  • 19 Feb, 2024
Comprehensive Genomic Profiling and Next Generation Functional Drug Screening for Patients With Aggressive Haematological Malignancies

EXALT-2 is a prospective, randomized, three arm study for treatment decision guided either by either comprehensive genomic profiling, next generation drug screening or physician's choice

melanoma of the skin
basal cell carcinoma of the skin
cancer
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  • 19 Feb, 2024
Hyperlactatemia During and After Tumorcraniotomy

This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.

craniotomy
hyperlactatemia
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  • 19 Feb, 2024
A Prospective Single-Center Evaluation of SureForm Staplers in Robotic-assisted Colorectal Procedures

The primary objective of this study is to evaluate the performance of SureForm Staplers (60 and 45) for transection and/or creation of anastomosis during robotic-assisted colorectal procedures.

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  • 19 Feb, 2024
Marker Driven Selection of Patients for Prostate Biopsy and Management

The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood biomarkers is more effective at detecting prostate cancer than standard of care interpretation of mpMRI with the Prostate Imaging …

biopsy of prostate
testosterone
tumor markers
multiparametric magnetic resonance imaging
digital rectal examination
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  • 19 Feb, 2024
Health and Employment After Gastro Intestinal Surgery - HEAGIS2

The principal aim of this study is to create a validated and replicable intervention model for supporting patients who undergone surgery for esophageal and gastro intestinal cancer.

intestinal cancer
recurrent tumor
curative surgery
neoplasm recurrence
cancer diagnosis
  • 0 views
  • 19 Feb, 2024
Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90

NVP-BEP800, a new HSP90 inhibitor, has particularly interesting therapeutic potential and represents hope in cancer pathologies. While it is currently being tested for solid cancers, no preclinical study has yet demonstrated its effectiveness in acute lymphoblastique leukemia (ALL).

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  • 19 Feb, 2024
Clinical and Psycho-social Impact of COVID-19 Related Confinement on Patients With Digestive Tumors

This study evaluates the clinical impact of these care adaptation on patients under treatment for a digestive tumor. A special focus is made on quality of life and psycho-social impact of treatment modifications on patients diagnosed with metastatic colorectal cancer and metastatic pancreatic cancer.

digestive tumor
covid-19
metastatic pancreatic cancer
cancer
  • 0 views
  • 19 Feb, 2024
Future of Colorectal Cancer Surgery

Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women. Very often the diagnosis is made by either endoscopy/colonoscopy and the surgical treatment is carried out by a minimally invasive approach ("Keyhole"surgery).

rectal cancer
colorectal surgery
liver function tests
cancer surgery
cancer resection
  • 0 views
  • 19 Feb, 2024