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Found 1247 clinical trials
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars

Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and social exclusion.

supportive psychotherapy
scar
laser therapy
dermabrasion
  • 0 views
  • 19 Feb, 2024
  • 1 location
Respiratory Muscle Training (RMT) in ALS

Participants will be stratified into 2 groups based on baseline inspiratory muscle strength as determined by maximum inspiratory pressure (MIP): six participants with minimal to no respiratory weakness (i.e., MIP 70% predicted) and six participants with mild to moderate inspiratory weakness (i.e., MIP 40-70% predicted).

maximum inspiratory pressure
maximum expiratory pressure
respiratory muscle training
weakness
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open Label Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC

The purpose of this trial is to evaluate the safety, tolerability and efficacy of various doses of STP705 administered as Intralesional injection in subjects with isSCC. Goals To determine the safe and effective recommended dose of STP705 for the treatment of isSCC.

  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effect of a Low FODMAP Diet in Irritable Bowel Syndrome Patients

Tertiary care IBS patients will be recruited for a prospective low FODMAP intervention study, hereby focusing on the reintroduction phase of the diet, where patients are blindly challenged with different FODMAP groups administered as powder, to be added to the strict FODMAP exclusion phase. During the screening phase of two …

irritable bowel syndrome
fodmap diet
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

probe
analgesia
postoperative pain
intubation
lung ventilation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Early Signs of Efficacy of IL12-L19L19.

The primary objective of the study is to evaluate the safety of IL12-L19L19 and to establish MTD, as recommended dose (RD). The secondary objectives of the study are to assess early signs of efficacy, the determination of pharmacokinetic (PK) properties and the immunogenicity of IL12-L19L19.

high-frequency microsatellite instability
pet/ct scan
prednisone
levothyroxine
bilateral salpingectomy
  • 0 views
  • 19 Feb, 2024
  • 4 locations
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The scan will be used to see how the disease has spread. Both the treatment strategies and probable disease outcomes as relevant to clinical endpoints will be assessed. This study is open to Veterans only.

positron emission tomography
adenocarcinoma of prostate
adenocarcinoma
external beam radiation therapy
salvage therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness and Parental Substance Use

For the families assigned to the treatment as usual group, they will continue to receive case management services from their residential facilities. Families in both groups will be asked to fill out 3 surveys (one at the beginning of the program, one at the end of the program, and at …

  • 0 views
  • 19 Feb, 2024
  • 1 location
The Young Heart Study

The purpose of our project is to better understand the characteristics of the young patients with coronary artery disease presenting for cardiac catheterization at our institution and to put forth a program to optimize their risk factors with a focus on gender differences. We will assess traditional and non-traditional risk …

cardiovascular disease
coronary disease
arterial disease
heart study
atherosclerosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them …

stage iii grade 2 follicular lymphoma
rituximab
beta-hcg
grade 2 follicular lymphoma
human chorionic gonadotropin
  • 0 views
  • 19 Feb, 2024
  • 1 location