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Found 684 clinical trials
Biomarkers of CASH

The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the accuracy of advanced imaging in association …

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  • 19 Feb, 2024
COVID-19 Infection and Multiple Myeloma

Collect in an observational study the outcomes of COVID19 infection in MM patients across Europe.

multiple myeloma
covid-19
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  • 19 Feb, 2024
Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Background Researchers seek ways to study people s medical problems in order to teach and further general knowledge. The ability to assess and treat people with a wide range of diseases is critical to training people to be good doctors. It is also needed to keep medical staff up to …

apheresis
x-rays
urine test
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  • 19 Feb, 2024
Overweight and Obesity as Prognostic Factors for Survival in Children With Acute Lymphoblastic Leukemia

Background: Mexico City has one of the highest incidences and mortality rates of acute lymphoblastic leukemia (ALL) in the world and a high frequency of early relapses (17%) and early mortality (15%). Otherwise, childhood overweight and obesity are reaching epidemic proportions. They have been associated with poor outcomes in children …

aspiration
lymphoblastic leukemia
overweight and obesity
lymphoid leukemia
leukemia
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  • 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

The overall aim of this study will be to collect tumour biopsies, biomarkers present in the blood, and other biological specimens which can be used to try to understand why resistance to anti-cancer treatment occurs, and to develop predictive biomarkers of this resistance in patients with locally advanced and metastatic …

advanced melanoma
cancer
metastatic melanoma
cancer treatment
metastatic malignant melanoma
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  • 19 Feb, 2024
Cerebral Morbidity After Radiation Therapy for Brain Tumors

All types of brain tumours apart from glioblastoma will be included.

meningioma
cognitive impairment
glioblastoma
medulloblastoma
cognitive dysfunction
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  • 19 Feb, 2024
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years.

proinsulin
glucagon
somatostatin
cancer
insulin
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  • 19 Feb, 2024
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients

Current guidelines lack definitive evidences about the relative benefits of locoregional surgery for the primary tumor in de novo stage IV breast cancer. The aim of this study (SYSBTC-001) was to investigate the role of locoregional surgery for primary tumor in de novo stage IV breast cancer.

invasive breast cancer
stage iv breast cancer
metastasis
cancer
primary lesion
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  • 19 Feb, 2024
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Background Adrenocortical cancer (ACC) is a rare tumor. The prognosis is very poor for people with advanced stages of ACC. Some people may live with ACC for years; others live for just months.

adrenal
solid tumors
adrenocortical carcinoma
cancer
blood tests
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  • 19 Feb, 2024
Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers

This pilot research trial studies the antibody response to high-dose seasonal influenza vaccination in patients with myeloid malignancy receiving chemotherapy and healthy volunteers. Evaluating antibody response to high-dose seasonal influenza vaccine may serve as a basis for vaccine recommendations in patients with myeloid malignancies and provide insights into the status …

influenza
myeloid malignancy
cancer
leukemia
antibody response
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  • 19 Feb, 2024