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Found 54 clinical trials
LAT for Oligoprogressive NSCLC Treated With First-line OSImertinib

To determine whether in patients with EGFR mutated advanced NSCLC and osimertinib as first-line treatment, the (repeated) use of LAT to 3 OP lesions and continuation of first-line osimertinib, improves the median progression-free survival by more than 3 months (i.e.

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  • 19 Feb, 2024
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

carcinoma of the cervix
non-melanoma skin cancer
stage iv non-small cell lung cancer
cancer
immunomodulators
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  • 19 Feb, 2024
Development and Analysis of a Stool Bank for Cancer Patients

This study is aimed at understanding the impact of gut microbiota on efficacy of cancer therapies, in particular checkpoint inhibitors, and using the resulting information to design microbial immunotherapies. Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are …

immunotherapies
pembrolizumab
cancer immunotherapy
cancer treatment
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  • 19 Feb, 2024
The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China

Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed to achieve personalized neoadjuvant immunotherapy.

measurable disease
alk gene translocation
EGFR
pneumonectomy
cancer
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  • 19 Feb, 2024