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Found 1318 clinical trials
Pediatric Caudal Injection Volume on Optic Nerve Sheath Diameter and Cerebral Oxygenation

Such mild changes are compensated well by healthy individuals and no clinical sequel is seen, however at-risk populations may be affected. We aim to see how different amounts of fluid injected into the epidural space may change two clinical parameters affected by intracranial pressure to determine if a lower volume …

elective surgery
pediatric
caudal injection
optic nerve
  • 0 views
  • 19 Feb, 2024
Interactive Decision Aid for Men Diagnosed With Prostate Cancer

It is hypothesized that: 1) improved decision making and psychosocial outcomes for the IDA arms will be mediated by increased knowledge; 2) participants who are undecided about the treatment decision and those that have information-seeking decision styles will benefit most from the decision-aid interventions.

cancer diagnosis
  • 0 views
  • 19 Feb, 2024
Comparison of Karydakis and Limberg Flap Treatment of Pilonidal Sinus in Adolescent. a Prospective Randomised Study

Produces clinic findings with abscess and discharge in the sacrococcygeal region or painful sinus tract in the natal cleft. Its incidence rate among Turkish servicemen is reported to be 8.8% in a study. Although pilonidal sinus disease is common in men, this is the opposite in adolescence. Because adolescent girls …

sinus disease
abscess
chronic inflammation
pilonidal sinus
  • 0 views
  • 19 Feb, 2024
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The purpose of this Phase I study is to find the maximum tolerated dose of MTX110 (a water-soluble Panobinostat nanoparticle formulation) and Gadolinium that can be given safely in children with newly diagnosed diffuse midline gliomas. All patients enrolled in the study will receive infusion of MTX110 and Gadolinium delivered …

coagulation disorder
neutrophil count
serum pregnancy test
side effects of drugs
platelet count
  • 0 views
  • 19 Feb, 2024
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose to study the effectiveness of TMS as a therapy for impaired verbal communication. The hypothesis to be tested is that TMS combined with Constraint Induced Language …

mini-mental state examination
alzheimer's disease
deficit
cognitive impairment
  • 0 views
  • 19 Feb, 2024
Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery

It was initially proposed for analgesia of costal fractures, pulmonary lobectomy and thoracic vertebrae. The ESP block (ESPB) could probably be extended to a large number of surgical procedures. ESPB has so far not been investigated in lumbar spinae stenosis surgery.

lumbar spinal stenosis
pulmonary lobectomy
analgesia
blockade
stenosis
  • 0 views
  • 19 Feb, 2024
Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

The innovation of this study is the combination of immune checkpoint inhibitor, Camrelizumab, and targeted drug against VEGFR, Apatinib, as an inductive therapy to treat the patients with locally advanced OSCC, followed with radical surgery and post-operative radiotherapy/chemoradiotherapy, the major pathologic response and safety will be evaluated as the primary …

lymph node metastases
squamous cell carcinoma
vascular endothelial growth factor receptor 2
metastasis
squamous cell carcinoma of the head and neck
  • 0 views
  • 19 Feb, 2024
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Niraparib works by blocking a substance produced by the body (PARP enzymes) in a way that tumor cells can be killed, or made more susceptible to chemotherapy.

fallopian tube
metastasis
neutrophil count
tumor cells
muga scan
  • 0 views
  • 19 Feb, 2024
Premie DCD Imaging Intervention Study

At this appointment, children undergo MRI and neurodevelopmental testing. Children who are identified with DCD at this appointment will be invited to participate in this intervention study. Participants will have a 2nd MRI 12 weeks after the first scan. They will then receive 12 weekly sessions with an occupational therapist, …

  • 0 views
  • 19 Feb, 2024
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique

Lung impedance technology allows simple lung fluid monitoring, and found to be effective in HF patients who suffer from a similar problem. The study's aim is to establish a correlation between lung fluid assessed by impedance technique and x-ray examinations.

chest x-ray
covid-19
respiratory distress
x-rays
acute respiratory distress
  • 0 views
  • 19 Feb, 2024