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Found 5887 clinical trials
Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

The purpose of this project is to realize a randomized open-label study (EudraCT number: 2020-000120-19) to evaluate the safety and the anti-tumor activity of peptide(s)-based immunotherapy in an umbrella window pre-operative opportunity phase II study in patients with squamous cell carcinoma of the head and neck.

cavity
squamous cell carcinoma of the head and neck
neutrophil count
carcinoma in situ of cervix
metastasis
  • 0 views
  • 19 Feb, 2024
A Study Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma

This is a first-in-human Phase I, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, and pharmacokinetics of RO7297089 and make a preliminary assessment of anti-tumor activity in patients with R/R MM for whom no established therapy for MM is appropriate and available or who are intolerant to …

measurable disease
multiple myeloma
refractory multiple myeloma
  • 0 views
  • 19 Feb, 2024
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

metastatic lung adenocarcinoma
bilateral oophorectomy
tubal ligation
kras
nivolumab
  • 0 views
  • 19 Feb, 2024
Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial (FUMS-EDJS2024)

Be monitored for tumor recurrence, side effects, and survival for up to 2 years after treatment.This is a single-arm, multicenter study involving 58 patients across several hospitals in China.

  • 0 views
  • 14 Jun, 2025
Infigratinib in Recurrent Glioblastoma Patients

Participants will be administered infigratinib prior to surgical resection of their tumor.

malignant glioma
red blood cell transfusion
FGFR3
contrast-enhanced magnetic resonance imaging
local pathology review
  • 0 views
  • 19 Feb, 2024
Pilot Study of the Haymakers for Hope Fitness Program

This research study is assessing the effect of an exercise program on cancer survivors. The exercise program is Haymakers for Hope 16-week exercise program

melanoma
neuropathy
cancer diagnosis
brain metastases
metastasis
  • 0 views
  • 19 Feb, 2024
Thyroid Cancer and Photoacoustic Imaging

In addition, we would like to confirm the relationship between the results of photoacoustic imaging and histopathologic findings when thyroid nodules were diagnosed as thyroid cancer.

photoacoustic imaging
cancer
thyroid nodule
  • 0 views
  • 19 Feb, 2024
Systematic Radioiodine Administration (3.7 GBq I131 After rhTSH) Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up

This trial is comparing two strategies in intermediate-risk differentiated thyroid cancer patients: Systematic radioiodine administration (3.7 GBq I131 after rhTSH) versus decision of radioiodine treatment guided by a post-operative work-up based on serum Tg values and diagnostic RAI scintigraphy

hurthle cell carcinoma
thyrotropin alpha
thyroglobulin
rtsh
differentiated thyroid cancer
  • 0 views
  • 19 Feb, 2024
2-Hydroxybenzylamine (2-HOBA) to Prevent Early Recurrence of Atrial Fibrillation After Catheter-based Ablation

Early recurrence of AF will be measured by ECGs that are recorded once per day by a smartwatch (Apple Watch, Apple Inc., Cupertino, CA) with additional ECGs recorded by the participant if they experience symptoms of AF, or if the smartwatch alerts the participant of a possible AF episode via …

fibrillation
  • 0 views
  • 19 Feb, 2024
Restrictive Use of Dexamethasone in Glioblastoma

Despite these findings, the suspicion of GBM often triggers the administration of DEX in routine clinical practice, regardless of neurological symptoms, tumor size, or extension of cerebral edema. The purpose of this study is to assess whether selected GBM patients can be treated safely with a restrictive DEX regimen from …

neurologic symptoms
glioblastoma multiforme
immunosuppression
dexamethasone
  • 0 views
  • 19 Feb, 2024