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Found 593 clinical trials
First-in-Human Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a first-in-human, Phase 1b, open-label trial to characterize the safety, tolerability, pharmacokinetics (PK), and biological activity of escalating doses of ATRC-101, an engineered, fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally-occurring human antibody.

cancer
breast cancer
cancer treatment
colorectal cancer
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

This study will investigate the effects of atezolizumab on select cancer types in people whose analysis of tumour DNA and RNA indicates they may be sensitive to atezolizumab. This study aims to determine if the information from the cancer genome analysis corresponds with the effects of atezolizumab on individuals and …

lung cancer
cancer
measurable disease
granulocyte colony stimulating factor
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

lung cancer
cancer
small cell lung cancer
measurable disease
bladder cancer
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Predicting Long-Term Clinical Outcomes in Chinese Breast Cancer Patients Receiving Neoadjuvant Chemotherapy  

At present, the majority of studies on neoadjuvant chemotherapy (NAC) in patients with breast cancer (BC) use pathological complete response (pCR) as a surrogate marker for patient prognosis, with significant improvements in pCR indicating better long-term survival.

  • 0 views
  • 11 Mar, 2025
Using Deep Learning Methods to Analyze Automated Breast Ultrasound Images to Establish a Diagnosis Therapy Assessment and Prognosis Prediction Model of Breast Cancer.

The purpose of this study is using a deep learning method to analyze the automated breast ultrasound (ABUS) imagings, establish and evaluate a diagnosis, therapy assessment and prognosis prediction model of breast cancer. The model would provide important references for further early prevention, early diagnosis and personalized treatment.

ultrasound breast
early detection
  • 0 views
  • 19 Feb, 2024
  • 1 location
AXillary Surgery After NeoAdjuvant Treatment

The optimal surgical axillary staging technique in patients who convert from the clinically positive to clinically negative lymph node status under neoadjuvant therapy (cN+ ycN0) remains to be clarified. Different strategies (axillary lymph node dissection, sentinel node biopsy, targeted axillary dissection) are currently used in different countries. A prospective analysis …

axillary lymph node dissection
sentinel lymph node biopsy
lymphadenectomy
invasive breast cancer
core needle biopsy
  • 0 views
  • 19 Feb, 2024
  • 9 locations
Antler Plate on Preventing Mammary High-risk Lesions From Malignant Development

This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

advanced breast cancer
breast neoplasm
HER2
breast mass
locally advanced breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
BIOPSY SCANNER LLTECH Technology for Diagnosis of Breast Cancer

Breast cancer is a frequent pathology and the speed of initial diagnosis makes it possible to improve the course of care and to reduce the anxiety of the patients.

immunohistochemistry
breast imaging reporting and data system
biopsy of breast
  • 0 views
  • 19 Feb, 2024
  • 1 location
Guardant360 Related Clinical Outcomes in Patients Who Share Medical Records-Breast Cancer

The purpose of this study is to observe the routine clinical care of patients who have been diagnosed with breast cancer and have undergone Guardant360 testing.

cancer
breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location