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Found 523 clinical trials
Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition

This is a multicenter, randomized controlled, phase III clinical trial. The purpose of this study is to evaluate the efficacy of standard nutrition treatment versus conventional nutrition treatment in local advanced nasopharyngeal carcinoma patients.

malnutrition
karnofsky performance status
renal function test
nutritional support
digestive system disease
  • 0 views
  • 19 Feb, 2024
A Long Term Follow-Up Study of Fabry Disease Subjects Treated With FLT190

The GLA enzyme is ubiquitously expressed throughout the body and is responsible for the breakdown of glycosphingolipids, deficiency of which results in the accumulation of specific glycosphingolipids that are associated with the pathophysiology of the disease.

breakdown
fabry's disease
deficiency
gene therapy
glycosphingolipids
  • 0 views
  • 19 Feb, 2024
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

This phase I/II trial studies the side effects and best dose of avelumab with M6620 in treating patients with deoxyribonucleic acid (DNA) damage repair (DDR) deficient solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). DDR deficiency refers to a …

MSH2
metastatic castration-resistant prostate cancer
cancer treatment
estrogen
fancc
  • 0 views
  • 19 Feb, 2024
Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents

Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol. The purpose of the clinical trial is to evaluate and compare the effects of slow and rapid activation rates of miniscrew-supported expanders on the skeletal changes, dento-alveolar changes and …

maxillary expansion
  • 0 views
  • 19 Feb, 2024
Prehabilitation for Gastrectomy

Prehabilitation has been demonstrated to be an effective strategy to improve outcomes in patients undergoing some of the abdominal operations. It may increase the physical capacity of the patient, improve postoperative quality of life and even decrease the postoperative morbidity. Currently, the most effective strategy seems to be a trimodal …

gastrectomy
cancer
gastric cancer
  • 0 views
  • 19 Feb, 2024
Iodine Impact on Thyroid Function and Psychomotor Development Observational Study in the Portuguese Minho Region

Full intellectual capabilities are achieved only if crucial nutrients are present during development. Iodine deficiency is the most common cause of preventable brain harm in infants. Because of its critical need during pregnancy, several countries implemented programs of iodine supplementation in preconception and pregnancy.

thyroid function
thyroid hormones
thyroid function test
thyroid hormone
deficiency
  • 0 views
  • 19 Feb, 2024
Malnutrition in Chronic Gastrointestinal Diseases Cross-sectional Study

Malnutrition and muscle wasting increase the risk of complications, reduce the life expectancy and impair the quality of life. The development of malnutrition and muscle wasting is different, as is the diagnosis and nutritional treatment.

magnetic resonance cholangiopancreatography
mrcp
short bowel
short bowel syndrome
liver cirrhosis
  • 0 views
  • 19 Feb, 2024
Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu Dhabi

The main objective of our project is to investigate the evolution of psychosocial, cardiovascular and immune markers in healthcare with different levels of exposure to the COVID-19 pandemic.

covid-19
  • 0 views
  • 19 Feb, 2024
Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency

To date, the investigators lack characterization of, the burden of, and the systemic progression of disease in ENPP1 deficiency and ABCC6 deficiency from a patient and/or parent perspective. This study aims to document this characterization, progression as well as the burden of disease.

  • 0 views
  • 19 Feb, 2024
Pompe Pregnancy Sub-Registry

The objective is to track pregnancy outcomes in women with Pompe Disease and to follow infants born to women with Pompe Disease.

  • 0 views
  • 19 Feb, 2024
  • 12 locations