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Found 49 clinical trials
A Study to Evaluate the Safety Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

acetylcholinesterase
mental state examination
alzheimer's disease
mild cognitive impairment
acetylcholinesterase inhibitor
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  • 19 Feb, 2024
Observational Study for the Evaluation of the Role of HIV-1 Tat Protein and Anti-Tat Immune Response In HIV Reservoir

A longitudinal observational study in HIV-infected subjects receiving cART addressed to explore the effect of the Tat protein and anti-Tat immunity on the formation and maintenance of HIV-1 virus reservoir.

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  • 19 Feb, 2024
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects

Background The immune system defends the body against disease. It has many different parts spread out in the body, including in the blood and skin. To learn more about it, researchers want to study samples from people with healthy immune systems and people with conditions that affect how the immune …

gastrointestinal symptoms
endoscopies
dermatitis
episodic fever
autoimmune disease
  • 0 views
  • 19 Feb, 2024
Smell and Taste Disorders in COVID-19 Patients

This is a prospective monocentric observational study with the aim of investigating the demographic and clinical factors related to the smell and taste disorders in patients with Severe Acute Respiratory Syndrome - Coronavirus - 2 (Sars-Cov-2) infection.

coronavirus infection
nasopharyngeal swab
acute respiratory syndrome (sars)
SARS
  • 0 views
  • 19 Feb, 2024
Rheumatology Patient Registry and Biorepository

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

dermatomyositis
rheumatic diseases
psoriatic arthritis
spondylitis
arteritis
  • 0 views
  • 19 Feb, 2024
Influenza Vaccination in Patients Living With HIV in the Northern Region

Anyone living with the Human Immunodeficiency Virus (HIV) has an indication for annual influenza vaccination. (Vaccination schedule and vaccination recommendations 2019). Influenza is a viral infection that has a significant impact on the health care system.

HIV Infection
immunodeficiency
influenza
influenza vaccination
trivalent influenza vaccine
  • 0 views
  • 19 Feb, 2024
Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers

This pilot research trial studies the antibody response to high-dose seasonal influenza vaccination in patients with myeloid malignancy receiving chemotherapy and healthy volunteers. Evaluating antibody response to high-dose seasonal influenza vaccine may serve as a basis for vaccine recommendations in patients with myeloid malignancies and provide insights into the status …

cancer
leukemia
myeloid malignancy
influenza
vaccination
  • 0 views
  • 19 Feb, 2024
Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO

The prognosis of patients with severe COVID-19 disease, whose lungs are so severely diseased that they need to be supported by veno-venous ECMO (extracorporeal membrane oxygenation), is difficult to assess so far. Previously published data from studies, case reports and case series describe a very high mortality in this patient …

membrane oxygenation
SARS
covid-19
acute respiratory syndrome (sars)
extracorporeal membrane oxygenation
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  • 19 Feb, 2024
Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care

This study aims to evaluate two ways to help people re-engage with healthcare. The first is to assess if providing HIV treatment on the first visit (or within 1 week) can help people re-engage with care and ultimately stay in care after 24 and 48 weeks. It will also assess …

HIV Infection
behavior modification
behavior therapy
  • 0 views
  • 19 Feb, 2024