glioblastoma multiforme Clinical Research Trials

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Found 502 clinical trials

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Phase 2
For Seniors
For adults
Recruiting in 10s
Interventional Study
all
Neurology
Recruiting

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

gliosarcoma

bevacizumab

PCR test

astrocytoma

vasectomy

0 views
19 Feb, 2024

Phase 3
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Neurology
Recruiting

ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM)

To confirm the result of previous Phase I/II and phase II clinical trials, this trial is to test the efficacy and safety of ADCTA immunotherapy plus the standard therapy in comparison with standard therapy alone in patients with recurrent GBM.

recurrent glioblastoma

thromboplastin

glioblastoma multiforme

karnofsky performance status

supratentorial tumor

0 views
19 Feb, 2024

Phase 1
For Seniors
For adults
Recruiting in 100s
Interventional Study
all
Neurology
Recruiting

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

For Phase 1, the purpose of this study is to assess the maximum tolerated dose (MTD), recommend phase 2 dose (RP2D), preliminary efficacy, and safety of selinexor in combination with SoC therapy for newly diagnosed glioblastoma multiforme (GBM) (nGBM) or recurrent GBM (rGBM). The study will independently evaluate 3 different …

recurrent glioblastoma

MRI

ccnu

neutrophil count

brain tumor

0 views
19 Feb, 2024