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Found 1042 clinical trials
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Secondary Aims Compare the efficacy of Everolimus plus Mycophenolate Mofetil versus Tacrolimus plus Mycophenolate Mofetil therapy as measured by the following: Biopsy-confirmed acute rejection Hyperlipidemia Proteinuria % regulatory T-cells in circulation NODAT [New Onset Diabetes mellitus After Transplant], hypertension and malignancy Tolerance measured by gene profiling at year 1, 2 …

chronic disease
renal toxicity
diabetes
renal failure
hepatitis b
  • 0 views
  • 19 Feb, 2024
Effectiveness of a Cardiovascular Risk Intervention Program in Patients With Schizophrenia (PRISCA)

Secondary measures: they will be determined, at baseline and at six-month follow-up, four cardiovascular risk factors as well: hypertension, hypercholesterolemia, hyperglycaemia and smoking, according with the latest recommendations of the Program of preventive activities and health promotion (PAPPS) of the Spanish Society of Family and Community Medicine.

hypertension
intervention program
hyperglycemia
schizophrenia
hypercholesterolemia
  • 0 views
  • 19 Feb, 2024
Preoperative Percutaneous RVAD to Preemptively Treat Right Heart Failure Post-LVAD

Since RVF is difficult to predict and can have harmful effects such as increased ICU stay, adverse outcomes, and mortality, it could be beneficial to preemptively treat patients through preoperative percutaneous right ventricular assist device (RVAD) placement to prevent RVF.

ventricular dysfunction
right ventricular failure
  • 0 views
  • 19 Feb, 2024
Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.

The investigators will then evaluate what impact the different transition experiences have on young people's health and wellbeing, and whether the process of Managed Transition has any benefits as compared to usual care.

psychiatric disorder
  • 0 views
  • 19 Feb, 2024
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

The investigators hypothesize that people with chronic stroke will show a slower rate of acquiring this leg skill as compared to healthy adults. The investigators also hypothesize that co-applying brain stimulation with 12 sessions of exercise training will enhance skill learning of this leg task for people with chronic stroke …

hemiparesis
mini-mental state examination
range of motion exercise
ischemic brain injury
brain stimulation
  • 0 views
  • 19 Feb, 2024
Acute Atrial Fibrillation and Flutter Treated Electively

After the months follow-up all patients are subsequently monitored for a maximum of five years for need of medical interventions due to atrial fibrillation of atrial flutter. New antiarrhythmics such as flecainide are not prescribed during the first month.

atrial flutter
thromboembolism
antiarrhythmic drug
fibrillation
cardioversion
  • 0 views
  • 19 Feb, 2024
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

On Arm B of the study, research participants will receive CAR T cells directed at B7H3 and CD19, a marker on the surface of B lymphocytes, following the hypothesis that CD19+ B cells serving in their normal role as antigen presenting cells to T cells will promote the expansion and …

biologic therapy
stem cell infusion
i131 mibg therapy
solid tumour
stem cell transplantation
  • 0 views
  • 19 Feb, 2024
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

nedaplatin
fluorouracil
metastasis
karnofsky performance status
liver function tests
  • 0 views
  • 19 Feb, 2024
Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer

Prostate cancer is the second most common cancer among Canadian men of which approximately 20-30% present with high-risk tumour characteristic. Although surgery can be curative in patients evidencing pathological high-risk disease (extracapsular extension, seminal vesicle involvement, positive surgical margins), a large proportion will develop biochemical failure within years from the …

bone metastases
metastasis
immunological adjuvant
gonadotropin releasing hormone
eligard
  • 0 views
  • 19 Feb, 2024
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

stereotactic body radiation therapy
carcinoma
hepatocellular carcinoma
radiofrequency ablation
recurrent hepatocellular carcinoma
  • 0 views
  • 19 Feb, 2024