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Found 1317 clinical trials
A Study to Look at How Safe NNC0472-0147 is in Healthy People and in People With Type 2 Diabetes

Participants will get once daily injections of either NNC0472-0147 or insulin glargine for a treatment period of fourteen days. The injections will be given under the skin (subcutaneously, s.c.) of the left thigh. Participants will be in the study for about 7 weeks. There will be 15 visits with the …

oophorectomy
type 1 diabetes mellitus
type 2 diabetes mellitus
cholesterol level
diabetes
  • 0 views
  • 19 Feb, 2024
Molecular Imaging of Prostate Cancer Using Radiofluorinated PSMA Ligand

Results of tracer uptake and MRI image features as whole body PET/MRI and dedicated pelvic/prostate PET/MRI, alone and together, will be correlated and compared to detection of lesions on conventional imaging modalities. Additionally, if the patient undergoes a biopsy as standard of care, image features will correlate directly with histopathological …

prostate specific antigen
metastasis
molecular imaging
localized disease
pet/mri
  • 0 views
  • 19 Feb, 2024
Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness and Parental Substance Use

Our primary hypothesis is that the adapted family resilience program will be feasible and acceptable to families with a recent history of homelessness and parental substance use disorder. Families that are eligible to participate in the study will be assigned randomly to one of two groups, 1) adapted family resilience …

  • 0 views
  • 19 Feb, 2024
Mobile App as a Guide to Exercises for Patients With Chronic Stroke

Even if chronicity leads us to think about the stabilization of the physical condition, It is thought that the best results will be found among the subjects who will use the App.

stroke
hemiparesis
hemiplegia or hemiparesis
physical rehabilitation
hemiplegia
  • 0 views
  • 19 Feb, 2024
Test Food4GutMarKIT - Evaluation of a Tailored Personalized Food Concept for a Healthy Gut Microbiota and Validation of Biomarkers for Monitoring of Its Effects  

The study will be running over 18 weeks (including a 6-week wash-out period) and it will include 9 visits at the clinic.

Accepts healthy volunteers
  • 0 views
  • 19 Feb, 2024
  • 3 locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

fulvestrant
solid tumour
hair thinning
her2-negative breast cancer
stage iv breast cancer
  • 0 views
  • 19 Feb, 2024
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Phase 3 is a randomized open-label crossover study comparing the final oral ASTX030 tablet to SC azacitidine. The duration of the study is expected to be approximately 36 months.

cytotoxic chemotherapy
myelodysplastic/myeloproliferative disease
leukemia
acute myeloid leukemia
immunosuppressive agents
  • 0 views
  • 19 Feb, 2024
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

KEAP1/NRF2 mutation status (for eligibility) and STK11/LKB1 status (for stratification) will be determined by next generation sequencing. A commercial liquid biopsy (circulating tumor DNA) NGS test will be provided to study participants free of charge.

NTRK
proto-oncogene tyrosine-protein kinase ros
folic acid
carboplatin
adjuvant therapy
  • 0 views
  • 19 Feb, 2024
NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

The purpose of this Phase I study is to determine the recommended phase 2 dose (RP2D) and safety profile of NBTXR3 activated by radiation therapy for the treatment of patients with pancreatic cancer that has spread to nearby tissues or lymph nodes (locally advanced) or may be able to be

paclitaxel
leucovorin
endoscopic ultrasound
resectable pancreatic cancer
celiac disease
  • 0 views
  • 19 Feb, 2024
Multi-mode Stroke Rehabilitation System: Development and Validation of Clinical Efficacy

The specific study aims will be: To develop the novel, digital, and interactive MSR system of arm and hand with integrated digital action observation therapy (AOT) and mirror therapy (MT).

aphasia
stroke rehabilitation
stroke
  • 0 views
  • 19 Feb, 2024