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Found 1064 clinical trials
Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer

This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients with prostate cancer. All patients in the study will receive EPI-7386. Since this is the first study of EPI-7386 in humans, there is no information about how it affects people …

metastatic castration-resistant prostate cancer
bone lesion
progressive disease
bone scan
metastasis
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Every 3 minutes a new case of diabetes is diagnosed in Canada, mostly type 2 diabetes (T2D) increasing the risk for heart disease. T2D and heart disease share many common risk factors such as aging, obesity and unhealthy lifestyle. Paradoxically however, while lowering blood LDL, commonly known as "bad cholesterol", …

omega-3 fatty acids
insulin
insulin sensitivity/resistance
fish oil
fatty acids
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

Thus, it is urgent to develop innovative models of PA, closer to patients and adjusted to the patients' routines, to engage and change patients' physical activity levels, enhancing HRQoL. iLiFE might be promising as it focuses on establishing new behaviours, within selected contexts to stimulate home-based PA. Therefore, iLiFE will …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Inspiratory Muscle Training Versus Calf Muscle on Venous Function

Fourty-two volunteer patients with venous insufficiency will include in the study were randomly divided into three groups as inspiratory exercise, calf muscle exercise and control. While the control group will receive only compression therapy, the inspiratory exercise group will apply inspiratory muscle training consisted of strengthening exercise in addition to …

exercise therapy
compression therapy
venous insufficiency
duplex ultrasound
6 minute walk test
  • 0 views
  • 19 Feb, 2024
  • 1 location
ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation

As part of the ROCO project, the University of Bern is investigating an online self-help program for people who are psychologically distressed due to the situation surrounding Covid-19.

covid-19
psychological stress
  • 0 views
  • 19 Feb, 2024
  • 1 location
Ultrasound Features of Dupuytren's Disease (Micro in DD)

This study will provide some insight into the use of US for DD and will primarily try to evaluate different parameters measurable with US that can be used as potential prognostic biomarkers.

  • 0 views
  • 07 May, 2025
  • 1 location
Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial (FUMS-EDJS2024)

This is a Phase II clinical trial to evaluate the efficacy and safety of perioperative toripalimab (anti-PD-1) combined with recombinant human endostatin (Endostar) as postoperative adjuvant therapy in patients with clinical stage II cutaneous or acral malignant melanoma. The study aims to answer:Does this combination improve the 2-year recurrence-free survival …

  • 0 views
  • 14 Jun, 2025
Effectiveness of a Mobile Neurofeedback for ADHD Youth

However, the Sham control group were provided the same machines and programs as the Neurofeedback exercise, but feedback is generated randomly regardless of ectroencephalogram change of the subjects.

atomoxetine
sham treatment
methylphenidate
neuropsychological test
attention deficit hyperactivity disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

This phase II trial studies how well decitabine with ruxolitinib or fedratinib works before hematopoietic stem cell transplant in treating patients with accelerated/blast phase myeloproliferative neoplasms (tumors). Drugs used in chemotherapy, such as decitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, …

polycythemia
cancer
hydroxyurea
white blood cells
myelodysplastic/myeloproliferative neoplasm
  • 0 views
  • 19 Feb, 2024
  • 1 location
Physiological Changes Induced Through MEP Conditioning in People With SCI

The study team is currently recruiting volunteers who are interested in participating in a brain-spinal cord-muscle response training study that aims to better understand the changes that take place in the nervous system as a result of this type of training. After spinal cord injury, brain-to-muscle connections are often interrupted. …

weakness
neurologic findings
spasticity
spinal cord disorder
traumatic brain injury
  • 0 views
  • 19 Feb, 2024
  • 1 location