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Found 4780 clinical trials
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis

The dysregulation of lncRNA results in the occurrence and development of tumors, diabetes, sepsis and other diseases. Therefore, we detected lncRNA and mRNA expression profile in 26 blood samples of septic patients using Arraystar LncRNA Microarray.

septicemia
organ failure
dysregulated host response
cell injury
long non-coding rna
  • 0 views
  • 19 Feb, 2024
  • 1 location
Mechanisms of Post-Bariatric Hypoglycemia

Post-bariatric hypoglycemia (PBH) is an increasingly recognized syndrome that is incompletely understood. The purpose of this study is to increase our level of understanding by investigating mechanisms contributing to this condition. Participation in this study will take place over four visits, which will include the following Wearing of a continuous …

glucagon
hypoglycemia
hormone levels
tolerance test
acarbose
  • 0 views
  • 19 Feb, 2024
  • 1 location
Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population

Introduction: Second Generation Antipsychotics (SGAs) are widely used in the pediatric population. It is currently established that SGAs may induce undesirable metabolic adverse events (AEs) such as weight gain, metabolic changes in blood lipids or glucose with risk of potential cardiovascular morbidity and mortality. The Canadian Alliance for Monitoring Effectiveness …

blood test
pediatric
hematology test
  • 0 views
  • 19 Feb, 2024
  • 1 location
Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19.

Considering that the intensity of systemic microvascular changes in patients in the acute phase of COVID-19 could be related to disease progression and prognosis, the present cross-sectional and observational study aims to investigate the presence of endothelial dysfunction in these patients, also looking for to evaluate associations between the presence …

covid-19
SARS
endothelial dysfunction
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 1 location
The COVID-19 Disease and CARdiac Events Study

An observational study of consecutive patients testing positive for COVID-19 who require admission to hospital to determine the degree of myocardial injury through biomarkers and echocardiography and the impact of this on cardiovascular outcomes. The COVID-19 disease and CARdiac Events study (COVICARE).

myocardial injury
covid-19
SARS
acute respiratory syndrome (sars)
x-rays
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sequelae of Sars-CoV-2 Infections

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …

coronavirus infection
pneumonia
cardiovascular system
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 1 location
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis

Gastric Per-Oral Endoscopic Myotomy (G-POEM) is a procedure for the Treatment of Gastroparesis.

g-poem
pyloromyotomy
poem procedures
gastroparesis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly

Background With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in elderly, corresponding nearly to 40% of cases, and the most rapidly growing cause of death in the …

cognitive impairment
demented
frontotemporal lobar degeneration
dementia
mild cognitive impairment
  • 0 views
  • 19 Feb, 2024
  • 1 location
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

critically ill
covid-19
inflammatory response
respiratory tract infection
superinfection
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Patient-Directed Mobile Tool to Streamline the QoL Assessment and Monitoring in Urothelial Carcinoma (Urolife)  

The goal of this observational study is to select contents and tools for the future development of a web app aiming to support patients' navigation for empowering decision-making through a higher awareness of urothelial carcinoma and its treatments, improving also educational aspects.The main question it aims to answer is:What are …

  • 0 views
  • 22 May, 2025
  • 1 location