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Found 1039 clinical trials
ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation

As part of the ROCO project, the University of Bern is investigating an online self-help program for people who are psychologically distressed due to the situation surrounding Covid-19.

psychological stress
covid-19
  • 0 views
  • 19 Feb, 2024
Ultrasound Features of Dupuytren's Disease (Micro in DD)

This study will provide some insight into the use of US for DD and will primarily try to evaluate different parameters measurable with US that can be used as potential prognostic biomarkers.

  • 0 views
  • 07 May, 2025
Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial (FUMS-EDJS2024)

This is a Phase II clinical trial to evaluate the efficacy and safety of perioperative toripalimab (anti-PD-1) combined with recombinant human endostatin (Endostar) as postoperative adjuvant therapy in patients with clinical stage II cutaneous or acral malignant melanoma. The study aims to answer:Does this combination improve the 2-year recurrence-free survival …

  • 0 views
  • 14 Jun, 2025
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

This phase II trial studies how well decitabine with ruxolitinib or fedratinib works before hematopoietic stem cell transplant in treating patients with accelerated/blast phase myeloproliferative neoplasms (tumors). Drugs used in chemotherapy, such as decitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, …

stem cell transplantation
leukemia
secondary myelofibrosis
white blood cell count
leukapheresis
  • 0 views
  • 19 Feb, 2024
Physiological Changes Induced Through MEP Conditioning in People With SCI

The study team is currently recruiting volunteers who are interested in participating in a brain-spinal cord-muscle response training study that aims to better understand the changes that take place in the nervous system as a result of this type of training. After spinal cord injury, brain-to-muscle connections are often interrupted. …

thoracic injuries
spinal cord injury
spinal cord disorder
weakness
spinal cord
  • 0 views
  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

Doxapram is a respiratory stimulant that has been administered off-label to treat AOP. Doxapram, as add-on treatment, seems to be effective in treating AOP and to prevent invasive mechanical ventilation. It is unclear if a preterm infant benefit from doxapram treatment on the longer term.

lung disease
apnea
off-label
pulmonary disease
doxapram
  • 0 views
  • 19 Feb, 2024
Comparison and Clinical Utility of the Portable Pressure Measuring Device for Garment Pressure Measurement on Hypertrophic Scar by Burn Injury During Compression Therapy

The investigators developed a portable pressure measuring device using silicon piezoresistive pressure sensors. As PicoPress is the most accurate (i.e., lowest variation and error) manometric sensor for pressure measurement, the investigators used it to compare and examine the accuracy of the proposed device regarding in vitro pressure measurements.

burn scar
treatment of burn
hypertrophic
compression therapy
scar
  • 0 views
  • 19 Feb, 2024
Regulated Expiratory Breathing Method During Childbirth

Despite a positive experience both reported by women and midwives, investigators have so far only subjective feedback without objective measurable clinical impact. As a result, investigators are conducting this scientific study whose main objective is: To Evaluate the impact of a regulated expiratory breathing method on childbirth process .

vaginal delivery
cesarean section
  • 0 views
  • 19 Feb, 2024
Adenoid Cystic Carcinoma and Carbon Ion Only Irradiation

Despite their slow growth, re-irradiation is often necessary due to the high metastatic risk. Patients are usually irradiated with photons or, as here at the Heidelberg University Hospital, with a combination of carbon ions and photons. So far, there is no data from Europe available for the sole irradiation with …

  • 0 views
  • 19 Feb, 2024
Does Point of Care Ultrasound Change Needle Insertion Location During Routine Bedside Paracentesis?

The primary endpoint will be whether POCUS yielded a change in the needle insertion site, as defined by a location greater than 5cm from the anatomic site, at least 20% of the time. The results will further our understanding of POCUS in improving procedural safety, thereby adding to the currently …

paracentesis
thoracentesis
  • 0 views
  • 19 Feb, 2024