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Found 574 clinical trials
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe

  • To describe the safety profile of MenACYW conjugate vaccine and a licensed meningococcal vaccine.
  • ul>

    pertussis
    pneumococcal
    antibiotic therapy
    dtap
    hib vaccine
    • 0 views
    • 19 Feb, 2024
    • 29 locations
    Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe

  • To describe the safety profile of MenACYW conjugate vaccine and a licensed meningococcal vaccine.
  • ul>

    pertussis
    pneumococcal
    antibiotic therapy
    dtap
    hib vaccine
    • 0 views
    • 19 Feb, 2024
    • 29 locations
    Asian Diabetes Outcomes Prevention Trial

    The aim of this study is to identify patients with DM at high risk of CVD using elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (>125pg/mL), and (2) intensify therapy using renin-angiotensin system (RAS) antagonists, beta-blockers and sodium glucose co-transporter-2 inhibitors (SGLT2i) for primary prevention of cardiovascular events in this high-risk …

    coronary artery stenosis
    stroke
    myocardial infarction
    ejection fraction
    angiotensin
    • 0 views
    • 19 Feb, 2024
    • 1 location
    Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease

    Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease

    arterial disease
    stenosis
    heart disease
    angiography
    intravascular ultrasound
    • 2 views
    • 19 Feb, 2024
    • 15 locations
    The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With Frailty

    This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery. Half of the participants will be randomized into the exercise group, while the other half will be randomized into the control group.

    • 0 views
    • 19 Feb, 2024
    • 1 location
    First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

    Primary Objectives:

    <ul>
  • Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B
  • Dose Expansion Part B: To assess …

    line of therapy
    pomalidomide
    monoclonal protein
    multiple myeloma
    refractory multiple myeloma
    • 0 views
    • 24 Nov, 2025
    • 8 locations
    Effects of a Multimodal Exercise Program on Physical Performance and Muscle Function in Middle-aged Patients With T2DM  

    The findings are expected to support early intervention strategies for healthy aging and serve as a valuable reference for clinical practice and the development of public health policies.ul>ul>

    • 0 views
    • 02 Dec, 2025
    • 3 locations
    Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

    This research study involves the following investigational drugs:

    <ul>
  • Ipatasertib
  • Atezolizumab
  • ul>

    triple negative breast neoplasms
    absolute lymphocyte count
    lumpectomy
    g-csf
    white blood cell count
    • 0 views
    • 19 Feb, 2024
    • 1 location
    Cisplatin+Pembrolizumab+RT in Vulvar Cancer

    This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma.

    This research study involves the following:

    <ul>
  • Cisplatin (standard of care drug)
  • Pembrolizumab (investigational drug)
  • Radiation Therapy (standard …

    liver metastasis
    ffpe
    cisplatin
    international normalized ratio
    excisional biopsy
    • 0 views
    • 19 Feb, 2024
    • 1 location
    Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

    The names of the study interventions involved in this study are:

    <ul>
  • Sacituzumab govitecan (IMMU-132)
  • Pembrolizumab (Keytruda; MK-3475)
  • ul>

    liver metastasis
    triple negative breast neoplasms
    brain metastases
    central nervous system disorder
    programmed cell death 1 ligand 1
    • 8 views
    • 19 Feb, 2024
    • 1 location