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Found 4341 clinical trials
Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

This study compares gadolinium contrast-enhanced Abbreviated MRI (AMRI) to standard ultrasound for Hepatocellular Carcinoma (HCC) screening and surveillance in subjects with liver cirrhosis.

carcinoma
cirrhosis
hepatocellular carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Perioperative Toripalimab and Endostatin for Stage II Melanoma: A Phase II Trial (FUMS-EDJS2024)

Be monitored for tumor recurrence, side effects, and survival for up to 2 years after treatment.This is a single-arm, multicenter study involving 58 patients across several hospitals in China.

  • 0 views
  • 14 Jun, 2025
Infigratinib in Recurrent Glioblastoma Patients

Participants will be administered infigratinib prior to surgical resection of their tumor.

direct bilirubin
FGFR3
hysterectomy
gilbert's syndrome
red blood cell transfusion
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

The primary hypothesis is that pembrolizumab + lenvatinib is superior to SOC chemotherapy with respect to ORR per modified Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by blinded independent central review.

lenvatinib
monoclonal protein
antihypertensive agents
cetuximab
antihypertensive
  • 0 views
  • 19 Feb, 2024
  • 3 locations
An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties

<p>Chronic pain is a commonly occurring complication of cancer but access to the first-line recommended treatment (pain-focused cognitive behavioral therapy - CBT) is limited outside of specialist pain clinics in Sweden, and these clinics do not routinely accept people with cancer-related pain.

  • 0 views
  • 15 Jan, 2025
  • 1 location
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

concurrent radiochemotherapy
EGFR
induction chemotherapy
cancer
egfr blocker
  • 4 views
  • 19 Feb, 2024
  • 1 location
Prehabilitation for Gastrectomy

Prehabilitation has been demonstrated to be an effective strategy to improve outcomes in patients undergoing some of the abdominal operations. It may increase the physical capacity of the patient, improve postoperative quality of life and even decrease the postoperative morbidity. Currently, the most effective strategy seems to be a trimodal …

gastric cancer
gastrectomy
cancer
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Radical Radiotherapy and Chemotherapy Combined With Maintenance Chemotherapy in the Treatment of Stage N3 NPC

This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and safety of radical chemoradiotherapy plus oral capecitabine/teggio for 1 year in patients with N3.

carcinoma
capecitabine
nasopharyngeal carcinoma
chemoradiotherapy
alt/ast
  • 0 views
  • 19 Feb, 2024
  • 1 location
Bintrafusp Alfa in Previously Treated Patients With Recurrent and Metastatic (R/M) Non-keratinizing Nasopharyngeal Carcinoma (NPC)

This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).

serum bilirubin level
immunomodulators
serum aspartate aminotransferase
serum total bilirubin
bintrafusp alfa
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Hydroxychloroquine vs Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy

The researchers are doing this study to find out whether the study drug hydroxychloroquine can prevent infection with the COVID-19 virus, compared with placebo, in people who are receiving radiation therapy for their cancer. The placebo used in this study is a tablet that looks the same as the study …

cough
chills
systemic therapy
throat
anosmia
  • 0 views
  • 19 Feb, 2024
  • 7 locations